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SRP72

Official Full Name

signal recognition particle 72kDa
Overview

This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that;mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA;and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or;heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal;recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in;this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding;different isoforms have been found for this gene.
Synonyms

SRP72; signal recognition particle 72kDa; signal recognition particle 72kD; signal recognition particle 72 kDa protein;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SRP72-1477HCL	Recombinant Human SRP72 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SRP72-1078H	Recombinant Human SRP72 protein, GST-tagged	E.coli	GST	2-671aa	Inquiry
Rhesus Macaque	SRP72-4469R	Recombinant Rhesus monkey SRP72 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SRP72-4285R-B	Recombinant Rhesus Macaque SRP72 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	SRP72-4285R	Recombinant Rhesus Macaque SRP72 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Chicken	SRP72-1589C	Recombinant Chicken SRP72	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SRP72 Related Articles

SRP72 involved in several pathways and played different roles in them. We selected most pathways SRP72 participated on our site, such as Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRP72 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Protein export	secB;SRP68;SEC11A;SPCS1;SEC62;SEC61AL2;IMMP2L;SPCS3;SRP14

SRP72 has several biochemical functions, for example, 7S RNA binding, poly(A) RNA binding, signal recognition particle binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRP72 itself. We selected most functions SRP72 had, and list some proteins which have the same functions with SRP72. You can find most of the proteins on our site.

Function	Related Protein
7S RNA binding	SRP14;SRP19;SRP54A;SRP9;SRP54;PIGC;SRP68;SRP72;EXOSC2
poly(A) RNA binding	TXN;RBM7;CD3EAP;ANP32A;RPL23;RDBP;AHNAK;UTP18;RPL30
signal recognition particle binding	SRP72;SRPR;SRP68;SRP9

SRP72 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRP72 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRP72.

HLA-B; PINX1; TULP3; FCHSD2; HSPB1; PYGM; SKIL; 1C; NPM1; Eif3a; RPL10; HNRNPU; ORC1; SNW1; BECN1

Yildirim-Ersoy, F; Ridout, CJ; et al. Detection of physically interacting proteins with the CC and NB-ARC domains of a putative yellow rust resistance protein, Yr10, in wheat. JOURNAL OF PLANT DISEASES AND PROTECTION 118:119-126(2011).