SRSF1
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Official Full Name
serine/arginine-rich splicing factor 1
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Synonyms
SRSF1;serine/arginine-rich splicing factor 1;SFRS1, splicing factor, arginine/serine rich 1;alternate splicing factor;ASF;MGC5228;pre mRNA splicing factor SF2;P33 subunit;SF2;SF2p33;splicing factor 2;SR splicing factor 1;SRp30a;ASF-1;alternative-splicing factor 1;splicing factor, arginine/serine-rich 1;pre-mRNA-splicing factor SF2, P33 subunit;SFRS1;FLJ53078;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- House Mouse
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Sf21 Insect Cell
- C
- Myc
- DDK
- Flag
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- MYC
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
SRSF1 involved in several pathways and played different roles in them. We selected most pathways SRSF1 participated on our site, such as Spliceosome, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | CDC40;HSC70;SNRPE;TTC6;SF3B14;U2SURP;SNRPD2;PPIL1;RBM25 |
| Herpes simplex infection | HLA-DOA;SKP2;NXF3;JAK2A;HLA-DQA1;MAPK10;SRSF1;CD74A;MAVS |
SRSF1 has several biochemical functions, for example, RNA binding, RS domain binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRSF1 itself. We selected most functions SRSF1 had, and list some proteins which have the same functions with SRSF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | ZRANB2;PPIE;RPL9;RBM8A;TRIM32;RNASEL4;TERT;BARHL1;RPS3 |
| RS domain binding | SRSF1;SRSF12;SRSF5;LUC7L;SRSF10 |
| mRNA binding | RC3H2;AGO2;DHFR;RBM25;RBPMS2B;D19BWG1357E;CCDC55;LUC7L2;CSTF2T |
| nucleotide binding | ATP2A2B;RBMX2;ACTC1A;ELAVL4;FIGN;MAPK14B;SLC27A3;PPP1R2P9;MAT2AA |
| poly(A) RNA binding | MPHOSPH10;SKIV2L2;PRR3;ZC3H10;ETF1;RRP1;DDX42;NXF3;NUSAP1 |
| protein binding | HSPB7;DEDD;APBA3;DMAP1;SLC22A7;CNKSR3;TRAPPC4;IGHMBP2;CD3E |
SRSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRSF1.
NXF1; SRPK1; Srpk1; NFYA; RNPS1
- Q&As
- Reviews
Q&As (5)
Ask a questionWhile there are no approved therapies specifically targeting SRSF1, preclinical studies are investigating its potential as a therapeutic target.
Studies suggest that SRSF1 expression levels could potentially serve as a biomarker for cancer diagnosis and prognosis.
Yes, SRSF1 has also been implicated in neurodegenerative diseases, such as spinal muscular atrophy.
SRSF1 regulates alternative splicing by binding to specific RNA sequences and influencing splice site selection.
SRSF1 interacts with other splicing factors and signaling proteins to regulate gene expression and cellular functions.
Customer Reviews (3)
Write a reviewTheir commitment to providing technical support is unparalleled, and their expertise can prove invaluable in navigating any challenges or troubleshooting that may arise during my experiments.
This commitment to staying at the forefront of research translates directly to the quality and performance of the SRSF1 protein in my trials.
They monitor the latest advancements in the field and incorporate new findings into the production and characterization of the protein.
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