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SRSF7

  • Official Full Name

    serine/arginine-rich splicing factor 7

  • Overview

    The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    SRSF7; serine/arginine-rich splicing factor 7; SFRS7, splicing factor, arginine/serine rich 7 (35kD) , splicing factor, arginine/serine rich 7, 35kDa; 9G8; AAG3; HSSG1; RBM37; SR splicing factor 7; ZCCHC20; ZCRB2; splicing factor 9G8; aging-associated p;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SRSF7-21H Recombinant Human SRSF7 protein, GST-tagged E.coli GST
Human SRSF7-1902HCL Recombinant Human SFRS7 293 Cell Lysate HEK293 N/A
Human SRSF7-22H Recombinant Human SRSF7 protein, His-tagged E.coli His 1-238 aa
Rhesus Macaque SRSF7-4477R Recombinant Rhesus monkey SRSF7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SRSF7-4293R Recombinant Rhesus Macaque SRSF7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SRSF7-4293R-B Recombinant Rhesus Macaque SRSF7 Protein Pre-coupled Magnetic Beads HEK293
Chicken SRSF7-3019C Recombinant Chicken SRSF7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SRSF7 Related Articles

SRSF7 involved in several pathways and played different roles in them. We selected most pathways SRSF7 participated on our site, such as Spliceosome, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRSF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
SpliceosomeMAGOH;RBM22;SNRPD1;CDC5L;PQBP1;SRSF1;LSM5;MAGOHB;SNRPD3
Herpes simplex infectionHLA-DOA;LTA;PPP1CBL;IFNB;UBE2R2;IFNB1;H2-Q10;MAPK10;FOS

SRSF7 has several biochemical functions, for example, nucleotide binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRSF7 itself. We selected most functions SRSF7 had, and list some proteins which have the same functions with SRSF7. You can find most of the proteins on our site.

Function Related Protein
nucleotide bindingSRSF2;NXF1;ATP8A1;UPF3A;NEK5;GNAI2A;CAMK2D2;PAK2B;RHOGA
poly(A) RNA bindingBST2;MEX3B;IGF2BP1;SRSF11;RPL7;C2orf15;ZCCHC17;HIST1H1B;NTPCR
protein bindingIL12A;TPI1;FOXB1;GPR50;RFC5;SF3A1;WNT11;IRAK4;OPRM1
zinc ion bindingKMT2A;KAT7;ZNF259;PEX2;UBR7;PDLIM1;MPI;RNF5;TRIM59

SRSF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRSF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRSF7.

NXF1; SDCBP; LUC7L2; RBBP6; SRPK2; SRPK1; Srek1

Robard, C; Daviau, A; et al. Phosphorylation status of the Kep1 protein alters its affinity for its protein binding partner alternative splicing factor ASF/SF2. BIOCHEMICAL JOURNAL 400:91-97(2006).
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