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AOC3

  • Official Full Name

    amine oxidase, copper containing 3 (vascular adhesion protein 1)

  • Overview

    Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone;cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has;functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb;downstream.
  • Synonyms

    AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); HPAO; SSAO; VAP1; VAP-1; membrane primary amine oxidase; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; EC 1.4.3.21; EC 1.4.3; Vepalimomab; 195158-85-1; Vapaliximab; 336801-86-6;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • CHO
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Sf21 Insect Cell
  • Spodoptera Frugiperda
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AOC3-564H Active Recombinant Human AOC3 protein, His-tagged Insect Cell His
Human AOC3-9402H Active Recombinant Human AOC3 protein CHO N/A
Human AOC3-641H Recombinant Human AOC3 protein, GST-tagged Wheat Germ GST
Human AOC3-85HCL Recombinant Human AOC3 cell lysate N/A
Human AOC3-1040H Recombinant Human AOC3 Protein, His-tagged HEK293 His
Human AOC3-1069HF Recombinant Full Length Human AOC3 Protein, GST-tagged In Vitro Cell Free System GST 763 amino acids
Mouse Aoc3-561M Active Recombinant Mouse Amine Oxidase, Copper Containing 3, His-tagged Spodoptera Frugiperda His
Mouse Aoc3-1015M Active Recombinant Mouse Aoc3 Sf21 Insect Cell N/A
Mouse AOC3-1724M Recombinant Mouse AOC3 Protein Mammalian Cell His
Mouse AOC3-591M-B Recombinant Mouse AOC3 Protein Pre-coupled Magnetic Beads HEK293
Mouse AOC3-591M Recombinant Mouse AOC3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat AOC3-693R Recombinant Rat AOC3 Protein Mammalian Cell His
Rat AOC3-349R-B Recombinant Rat AOC3 Protein Pre-coupled Magnetic Beads HEK293
Rat AOC3-349R Recombinant Rat AOC3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mus musculus (Mouse) RFL-9335MF Recombinant Full Length Mouse Membrane Primary Amine Oxidase(Aoc3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-765)
Rattus norvegicus (Rat) RFL-14285RF Recombinant Full Length Rat Membrane Primary Amine Oxidase(Aoc3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-763)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AOC3 Related Research Area

AOC3 involved in several pathways and played different roles in them. We selected most pathways AOC3 participated on our site, such as Glycine, serine and threonine metabolism, Tyrosine metabolism, Phenylalanine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AOC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycine, serine and threonine metabolismDLDH;PIPOX;SHMT2;PGAM1A;PGAM1B;GRHPRB;CTH;MAOB;GCSHB
Tyrosine metabolismDBH;HGD;AOX2P;AOX3;GOT2;PNMT;AOX4;AOC3;MIF
Phenylalanine metabolismGOT1;ALDH3A1;HPDB;MAOA;AOC3;ALDH3B2;IL4I1;ALDH3B1;PAH
beta-Alanine metabolismSMS;ACADM;ALDH9A1B;ALDH6A1;ALDH2;GAD1B;HADHAB;ALDH3A2A;ALDH9A1A.1
Metabolic pathwaysFBP1A;SDHA;ASPA;HIBCH;MGAT5;ATP6V0D2;POC1B-GALNT4;KHK;ATP6V1H

AOC3 has several biochemical functions, for example, aliphatic-amine oxidase activity, aminoacetone:oxygen oxidoreductase(deaminating) activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AOC3 itself. We selected most functions AOC3 had, and list some proteins which have the same functions with AOC3. You can find most of the proteins on our site.

Function Related Protein
aliphatic-amine oxidase activityAOC2;AOC3
aminoacetone:oxygen oxidoreductase(deaminating) activityAOC3;AOC2
calcium ion bindingFKBP10B;CDH4;CELSR1;SLC25A12;SYT1;CANX;C1rb;CALRL2;BRAF
copper ion bindingMOXD2;MT3;TP53;LOXL2B;LOXL3A;POLR1B;LOXL5B;METTL17;ABP1
phenethylamine:oxygen oxidoreductase (deaminating) activityAOC3;AOC2
primary amine oxidase activityVCAM1;AOC1;MAOB;ABP1;AOC2;MAOA;AOC3
protein bindingHIST1H4I;NUDT21;SETDB1;STMN2;IVL;ARHGEF15;ASNA1;RND3;UBE2H
protein heterodimerization activityCHUK;UGT1A2;ZHX3;NEUROD2;INHA;GRIN2A;HIST1H2BL;BAD;VOX
protein homodimerization activityMZF1;ASNSD1;PAFAH1B2;QPRT;DHDPSL;GM5506;DROSHA;CACYBP;ACTN4
quinone bindingAOC2;AMOTL1;ETFDH;AOC1;HHIP;ABP1;AOC3;VKORC1L1;NDUFS7
tryptamine:oxygen oxidoreductase (deaminating) activityAOC3;AOC2

AOC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AOC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of AOC3.

MYBPC2; PRRG4

  • Q&As
  • Reviews

Q&As (18)

Ask a question
Is AOC3 suitable for children? 12/21/2022

There is no clear data on the use of AOC3 in children, and more research is needed to determine its safety and efficacy.

What is AOC3 used for? 11/10/2022

AOC3 is an important enzyme that produces human myocardial peptides, which play a key role in heart function and blood pressure regulation.

Have there been relevant studies showing that AOC3 can improve cardiac function? 08/27/2022

Some studies have shown that AOC3 may have a certain improvement in cardiac function, but more clinical trials are needed to verify it.

What are the potential side effects of AOC3 therapy? 09/07/2021

It has not been fully determined, but some possible adverse effects include allergic reactions, digestive discomfort and headaches.

Is AOC3 suitable for all patients with cardiovascular disease? 08/09/2021

There is no clear data showing that AOC3 is suitable for all patients with cardiovascular disease, and the specific application scope needs further research.

Is the combination of AOC3 with other cardiovascular drugs safe? 08/02/2021

There is no clear data showing adverse interactions between AOC3 and other cardiovascular drugs, but it should be used in accordance with doctor's recommendations.

How to treat AOC3 ? 07/03/2021

At present, AOC3 therapy is mainly administered by injection.

Can AOC3 be used in the treatment of angina? 04/30/2021

AOC3 has certain potential for the treatment of angina pectoris, but the specific effect needs to be further verified.

Is there any research to explore the application of AOC3 in the treatment of pulmonary hypertension? 02/21/2021

Yes, some studies have explored the potential of AOC3 in the treatment of pulmonary hypertension, but more research is needed to determine its clinical effect.

How to determine the dose of AOC3 ? 01/08/2021

The determination of dosage is usually based on specific study design and treatment goals, and multi-center, large-sample studies are required to determine the optimal dose in clinical practice.

What is the progress of clinical trials on AOC3 ? 11/27/2020

Clinical trials of AOC3 are ongoing to evaluate its safety and efficacy in the treatment of different diseases.

How does AOC3 regulate blood pressure? 10/04/2020

AOC3 can reduce arterial blood pressure and reduce angiotensin II activity through degradation.

Does AOC3 have potential applications in rehabilitation after myocardial infarction? 09/01/2020

There is some evidence that AOC3 may have a certain application prospect in the rehabilitation process after myocardial infarction, but more research is needed to verify its clinical effect.

How long does the therapeutic effect of AOC3 last? 08/03/2020

Studies used in the treatment of pulmonary hypertension have shown that the therapeutic effect of AOC3 diminishes over time.

Is there any scientific research on the association between AOC3 and heart disease? 05/24/2020

There have been academic studies showing an association between AOC3 and heart disease, and it is involved in angiotensin production, left ventricular hypertrophy and angina pectoris.

How to evaluate the clinical efficacy of AOC3 ? 01/31/2020

The clinical efficacy of AOC3 is usually evaluated through multicenter, randomized controlled clinical trials.

Does AOC3 have clinical application? 01/27/2020

Yes, AOC3 has the potential to be used in the clinic to treat cardiovascular disease and related diseases such as hypertension.

Are there any AOC3 drugs on the market? 06/14/2019

There are currently no commercially available AOC3 drugs, but clinical trials are ongoing.

Customer Reviews (4)

Write a review
Reviews
07/16/2022

    I appreciate the Aoc3 manufacturer's attention to product quality, and their product repeatability is very good, which makes our experiment more smooth.

    12/11/2021

      Aoc3 can be stored at room temperature for several days without deterioration, which allows us to easily conduct experiments and obtain reliable results.

      05/25/2021

        Purity is very high, showing good production process and quality control.

        04/11/2020

          Solubility of Aoc3 demonstrated well in Western blots and can be easily dissolved in a variety of buffers.

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