SSBP1
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Official Full Name
single-stranded DNA binding protein 1
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Overview
SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 (PubMed 7789991)). It is also a;subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et;al., 2009) (PubMed 19683501). -
Synonyms
SSBP1; single-stranded DNA binding protein 1; single stranded DNA binding protein; single-stranded DNA-binding protein, mitochondrial; SSBP; PWP1-interacting protein 17; mtSSB; Mt-SSB; SOSS-B1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SSBP1-2965H | Recombinant Human SSBP1, GST-tagged | E.coli | GST | 1-148aa | |
| Human | SSBP1-29275TH | Recombinant Human SSBP1 | Wheat Germ | N/A | 148 amino acids |
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| Human | SSBP1-7584H | Recombinant Human SSBP1, His-tagged | E.coli | His | 17-148aa |
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| Human | SSBP1-1465HCL | Recombinant Human SSBP1 293 Cell Lysate | HEK293 | N/A |
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| Human | SSBP1-498HF | Recombinant Full Length Human SSBP1 Protein | In Vitro Cell Free System | 148 amino acids |
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| Mouse | SSBP1-16023M | Recombinant Mouse SSBP1 Protein | Mammalian Cell | His |
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| Mouse | SSBP1-8741M | Recombinant Mouse SSBP1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | Ssbp1-6140M | Recombinant Mouse Ssbp1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | SSBP1-8741M-B | Recombinant Mouse SSBP1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | SSBP1-5752R | Recombinant Rat SSBP1 Protein | Mammalian Cell | His |
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| Rat | SSBP1-5411R | Recombinant Rat SSBP1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | SSBP1-5411R-B | Recombinant Rat SSBP1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | SSBP1-4482R | Recombinant Rhesus monkey SSBP1 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | SSBP1-4298R-B | Recombinant Rhesus Macaque SSBP1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | SSBP1-4298R | Recombinant Rhesus Macaque SSBP1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | SSBP1-2539Z | Recombinant Zebrafish SSBP1 | Mammalian Cell | His |
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| Chicken | SSBP1-5289C | Recombinant Chicken SSBP1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
SSBP1 involved in several pathways and played different roles in them. We selected most pathways SSBP1 participated on our site, such as DNA replication, Mismatch repair, Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA replication | MCM3L;RFC1;RFC2;POLE3;RPA1;RPA3;MCM4;RFC4;MCM3 |
| Mismatch repair | SSBP1;RFC3;RPA2;PMS2;EXO1;POLD4;MSH6;POLD1;MSH2 |
| Homologous recombination | RAD51C;MUS81;RAD51L1;FUZ;NBN;XRCC3;TOP3A;TOP3B;BLM |
SSBP1 has several biochemical functions, for example, chromatin binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SSBP1 itself. We selected most functions SSBP1 had, and list some proteins which have the same functions with SSBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin binding | REL;NKX2;CDCA5;UPF1;SAFB;POLE;MSL1A;HDGF2;SOX15 |
| poly(A) RNA binding | RTF1;RRP9;RPS12;RPS3;DHX30;SAMD4;RPS15;MSI1;PPP1R10 |
| protein binding | NUMB;RTN4RL1;KLK4;RAB1B;ACTR10;COL17A1;MXD3;CDC42EP5;EXOC3-AS1 |
| single-stranded DNA binding | TDP2B;HNRNPDL;PURB;RAD51B;RAD23A;LRPPRC;MEIOB;TDP1;SSBP3 |
SSBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSBP1.
rev; Kif1c; Top3a; Cdk1; Cep170; Ercc6l; Haus1; Rmi1; Eurl; ere_dna
- Q&As
- Reviews
Q&As (5)
Ask a questionSSBP1 plays a crucial role in the cellular response to DNA damage by facilitating the repair of single-stranded DNA breaks, thereby maintaining genomic stability.
Researchers are exploring the potential of SSBP1 as a biomarker for cancer detection, as abnormal levels or mutations in this protein may indicate underlying DNA repair issues associated with cancer.
Apart from cancer, SSBP1 dysregulation has been associated with certain neurological disorders and autoimmune diseases, making it a potential target for therapeutic intervention.
Some studies suggest that targeting SSBP1 in cancer cells could be a potential therapeutic strategy, as it may sensitize cancer cells to DNA-damaging treatments.
Some research suggests a potential link between SSBP1 dysfunction and neurodegenerative diseases, indicating a broader impact on various aspects of cellular health.
Customer Reviews (3)
Write a reviewIts use in EM studies allows researchers to gain insights into the structural details of proteins and their complexes at high resolution.
Its versatility and reliability make it a great choice for researchers exploring protein dynamics, function, and interactions.
The manufacturer's support team provides extensive technical assistance, helping researchers navigate any challenges they may face throughout their experiments.
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