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SSTR4

  • Official Full Name

    somatostatin receptor 4

  • Overview

    transmembrane receptor for somatostatin; coupled to a G-protein which inhibits adenylyl cyclase; may also activate the mitogen-activated protein (MAP) kinase cascade
  • Synonyms

    SSTR4; somatostatin receptor 4; somatostatin receptor type 4; SS 4R; SS4R; SST R4; SSTR 4; SS4-R; SS-4-R; Somatostatin receptor subtype 4 Rattus norvegicus Sprague-Dawley major hippocampal somatostatin receptor (SSTR4) mRNA; Smstr4;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Homo sapiens (Human)
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Rat SSTR4-5763R Recombinant Rat SSTR4 Protein Mammalian Cell His
Rat SSTR4-5422R Recombinant Rat SSTR4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SSTR4-5422R-B Recombinant Rat SSTR4 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL21724HF Recombinant Full Length Human Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged E.coli expression system His Full Length (1-388)
Mus musculus (Mouse) RFL12898MF Recombinant Full Length Mouse Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Rattus norvegicus (Rat) RFL24711RF Recombinant Full Length Rat Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Chicken SSTR4-3163C Recombinant Chicken SSTR4 Mammalian Cell His
Kit-1046 ATP Colorimetric Assay Kit (384-well) N/A
Kit-1527 SSTR4 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1528 cAMP SSTR4 CHO-K1 GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SSTR4 Related Articles

SSTR4 involved in several pathways and played different roles in them. We selected most pathways SSTR4 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSTR4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)OPN4A;SSTR4;EDN1;PPY;SSTR5;CCR9;CCR6;GPR55;LPAR2A
G alpha (i) signalling eventsSST;TAS2R3;GPR17;RGS10;SSTR2;LPAR2A;PENK;PPY;RGS4
GPCR downstream signalingNMB;NTS;OR7D2;EDN2;OPN1LW;RAMP1;KALRN;CGA;EDN1
GPCR ligand bindingGPR17;OPN1LW1;PENKA;CRHB;AGT;PTGDR2;CCR9;OPN4B;EDN3
GPCRs, Class A Rhodopsin-likePTGDR2;GPR77;GPR65;HRH3;CHRM4;CCR3;NMUR1;CMKLR1;GPR75
Neuroactive ligand-receptor interactionTAAR6;GH1;P2RY14;NPFFR2.1;AVPR2;CHRM2A;GRIN1A;GLRA2;HCRTR2
Peptide GPCRsCX3CR1;SSTR5;SSTR4;TAC4;CXCR6;SSTR1
Peptide ligand-binding receptorsPENKB;NMBA;PYY;RLN3;CCL19A.2;GPR37B;CCL35.2;EDN3;CCL35.1

SSTR4 has several biochemical functions, for example, neuropeptide binding, somatostatin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SSTR4 itself. We selected most functions SSTR4 had, and list some proteins which have the same functions with SSTR4. You can find most of the proteins on our site.

Function Related Protein
neuropeptide bindingMRGPRB1;PTGDR2;MRGPRX2;MC4R;SSTR2;OPRK1;NPBWR2;SSTR1;NPBWR1
somatostatin receptor activitySSTR3;SSTR4;SSTR1;SSTR5;SSTR2

SSTR4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSTR4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSTR4.

Frati, A; Rouzier, R; et al. Expression of Somatostatin Type-2 and-4 Receptor and Correlation with Histological Type in Breast Cancer. ANTICANCER RESEARCH 34:3997-4003(2014).
Yamamoto, J; Ohnuma, K; et al. Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma. BRITISH JOURNAL OF CANCER 110:2232-2245(2014).
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