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ST3GAL3

  • Official Full Name

    ST3 beta-galactoside alpha-2,3-sialyltransferase 3

  • Overview

    plays a role in the formation of terminal carbohydrate groups of glycolipids and glycoproteins
  • Synonyms

    ST3GAL3; ST3 beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; ST3 beta galactoside alpha 2,3 sialyltransferase 3; 4GlcNAc alpha 2 3 sialyltransferase; Alpha 2 3 sialyltransferase II; Alpha 2 3 sialyltransferase III; Alpha 2 3 ST 3; Beta galactoside alpha3 sialyltransferase 3; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase; EC 2.4.99.6; Gal beta 1 3; Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase; Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase; N acetyllactosaminide alpha 2 3 sialyltransferase; OTTHUMP00000008820; OTTHUMP00000008821; OTTHUMP00000008822; OTTHUMP00000008823; Sialyltransferase 6; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase); SIAT6; ST3 beta galactoside alpha 2 3 sialyltransferase 3; ST3Gal III; ST3GALII; ST3GalIII; ST3N; alpha 2,3-ST 3; beta-galactoside alpha-2,3-sialyltransferase 3; N-acetyllacosaminide alpha 2,3-sialyltransferase; N-acetyllactosaminide alpha-2,3-sialyltransferase; gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; sialyltransferase (N-acetyllacosaminide alpha 23-sialyltransferase); sialyltransferase 6(N-acetyllacosaminide alpha 23-sialyltransferase); sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
  • N
  • 6×His, GFP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ST3GAL3-234H Recombinant Human ST3GAL3, GST-tagged Wheat Germ GST
Human ST3GAL3-232H Recombinant Human ST3GAL3, His-tagged E.coli His 218 to 359
Human ST3GAL3-233H Recombinant Human ST3GAL3, GST-tagged Wheat Germ GST
Human ST3GAL3-1441HCL Recombinant Human ST3GAL3 293 Cell Lysate HEK293 N/A
Human ST3GAL3-1002H Recombinant Human ST3GAL3 Protein (29-375 aa), His-SUMO-tagged E.coli His/SUMO 29-375 aa
Human ST3GAL3-502HF Recombinant Full Length Human ST3GAL3 Protein, GST-tagged In Vitro Cell Free System GST 390 amino acids
Human ST3GAL3-12H Recombinant Human ST3GAL3 Protein (AA 60-375), N-6×His/GFP tagged HEK293 N-6×His, GFP AA 60-375
Mouse ST3GAL3-16064M Recombinant Mouse ST3GAL3 Protein Mammalian Cell His
Mouse ST3GAL3-8760M-B Recombinant Mouse ST3GAL3 Protein Pre-coupled Magnetic Beads HEK293
Mouse ST3GAL3-8760M Recombinant Mouse ST3GAL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ST3GAL3-5768R Recombinant Rat ST3GAL3 Protein Mammalian Cell His
Rat ST3GAL3-5427R-B Recombinant Rat ST3GAL3 Protein Pre-coupled Magnetic Beads HEK293
Rat ST3GAL3-5427R Recombinant Rat ST3GAL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mus musculus (Mouse) RFL509MF Recombinant Full Length Mouse Cmp-N-Acetylneuraminate-Beta-1,4-Galactoside Alpha-2,3-Sialyltransferase(St3Gal3) Protein, His-Tagged E.coli expression system His Full Length (1-374)
Chicken ST3GAL3-5505C Recombinant Chicken ST3GAL3 Mammalian Cell His
Chicken ST3GAL3-5506C Recombinant Chicken ST3GAL3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ST3GAL3 Related Articles

ST3GAL3 involved in several pathways and played different roles in them. We selected most pathways ST3GAL3 participated on our site, such as Other types of O-glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - lacto and neolacto series, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST3GAL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Other types of O-glycan biosynthesisPOFUT1;MGAT5B;B4GALT3;B4GALT1;B3GALTL;C3orf64;FUT4;LFNG;POMT1
Glycosaminoglycan biosynthesis - keratan sulfateB3GNT2B;B4GALT1;B3GNT1;CHST1;CHST2;ST3GAL3;B3GNT7;CHST4;ST3GAL1
Glycosphingolipid biosynthesis - lacto and neolacto seriesFUT9;FUT9A;GGTA1;B3GNT1;FUT5;GCNT2;B3GALT5;ST8SIA1;FUT3
Metabolic pathwaysDNMT3AA;UXS1;NDUFA6;P4HA2;CMAS;AMY1B;ASL;UPRT;ATP5J

ST3GAL3 has several biochemical functions, for example, N-acetyllactosaminide alpha-2,3-sialyltransferase activity, beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST3GAL3 itself. We selected most functions ST3GAL3 had, and list some proteins which have the same functions with ST3GAL3. You can find most of the proteins on our site.

Function Related Protein
N-acetyllactosaminide alpha-2,3-sialyltransferase activityST3GAL3A;ST3GAL3;ST3GAL3B
beta-galactoside (CMP) alpha-2,3-sialyltransferase activityST3GAL1;ST3GAL5L;ST3GAL5;ST3GAL3;ST3GAL2L;ST3GAL4;ST3GAL2;ST3GAL3B;ST3GAL3A

ST3GAL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST3GAL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST3GAL3.

ZBTB5; SCAMP2; TTR; RPL8; ACTG1

Radhakrishnan, P; Chachadi, V; et al. TNF alpha enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 409:436-441(2011).
Hatzfeld, A; Eid, P; et al. A sub-population of high proliferative potential-quiescent human mesenchymal stem cells is under the reversible control of interferon alpha/beta. LEUKEMIA 21:714-724(2007).
  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the role of ST3GAL3 protein in nervous system development? 05/15/2021

ST3GAL3 proteins play an important role in the development of the nervous system, it is involved in the process of neuronal formation and synaptic connections, and is essential for the normal development and maintenance of the nervous system.

Are there multiple subtypes of ST3GAL3 genes? 12/30/2020

Yes, there are multiple subtypes of ST3GAL3 genes, which may have different functional and regulatory properties when encoding ST3GAL3 proteins.

What is the function of ST3GAL3 protein? 08/09/2020

The protein is a glycosyltransferase that participates in a glycosylation reaction that combines acetylneuraminic acid and sialic acid to form sialic acid-α-2,3-acetylneuraminominia. This glycosylation modification plays an important role in cell recognition and signaling.

What diseases are ST3GAL3 proteins associated with? 03/26/2020

ST3GAL3 protein has been linked to a variety of neurological-related diseases, including Parkinson's disease, Alzheimer's disease, Huntington's disease, and others. Abnormal expression or functional deficits may cause developmental and functional disorders of the nervous system.

Are there interactions between ST3GAL3 proteins and other molecules in the nervous system? 01/11/2020

There may be interactions between ST3GAL3 proteins and other molecules in the nervous system, such as with neuronal surface receptors or cell adhesion molecules, but the specific interaction network needs to be studied in depth.

What are the molecular mechanisms of ST3GAL3 proteins in neuronal development? 10/26/2019

ST3GAL3 proteins are involved in neuronal development by regulating signaling pathways related to cell adhesion, migration and synaptic formation, and the specific mechanism needs further study.

Customer Reviews (3)

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Reviews
05/05/2022

    The catalytic activity of this protein is very excellent, and it can be widely used in various chemical reactions, so its application prospects are very broad.

    04/20/2022

      Due to stability of ST3GAL3 is very strong, maintaining its structural and functional stability even after extensive use, which shows its excellent quality and reliability.

      08/03/2020

        ST3GAL3 are very safe and can be used with confidence.

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