ST3GAL3
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Official Full Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
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Overview
plays a role in the formation of terminal carbohydrate groups of glycolipids and glycoproteins -
Synonyms
ST3GAL3; ST3 beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; ST3 beta galactoside alpha 2,3 sialyltransferase 3; 4GlcNAc alpha 2 3 sialyltransferase; Alpha 2 3 sialyltransferase II; Alpha 2 3 sialyltransferase III; Alpha 2 3 ST 3; Beta galactoside alpha3 sialyltransferase 3; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase; EC 2.4.99.6; Gal beta 1 3; Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase; Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase; N acetyllactosaminide alpha 2 3 sialyltransferase; OTTHUMP00000008820; OTTHUMP00000008821; OTTHUMP00000008822; OTTHUMP00000008823; Sialyltransferase 6; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase); SIAT6; ST3 beta galactoside alpha 2 3 sialyltransferase 3; ST3Gal III; ST3GALII; ST3GalIII; ST3N; alpha 2,3-ST 3; beta-galactoside alpha-2,3-sialyltransferase 3; N-acetyllacosaminide alpha 2,3-sialyltransferase; N-acetyllactosaminide alpha-2,3-sialyltransferase; gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; sialyltransferase (N-acetyllacosaminide alpha 23-sialyltransferase); sialyltransferase 6(N-acetyllacosaminide alpha 23-sialyltransferase); sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase);
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- N/A
- N
- 6×His, GFP
- Involved Pathway
- Protein Function
- Interacting Protein
- ST3GAL3 Related Articles
ST3GAL3 involved in several pathways and played different roles in them. We selected most pathways ST3GAL3 participated on our site, such as Other types of O-glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - lacto and neolacto series, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST3GAL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Other types of O-glycan biosynthesis | POFUT1;MGAT5B;B4GALT3;B4GALT1;B3GALTL;C3orf64;FUT4;LFNG;POMT1 |
Glycosaminoglycan biosynthesis - keratan sulfate | B3GNT2B;B4GALT1;B3GNT1;CHST1;CHST2;ST3GAL3;B3GNT7;CHST4;ST3GAL1 |
Glycosphingolipid biosynthesis - lacto and neolacto series | FUT9;FUT9A;GGTA1;B3GNT1;FUT5;GCNT2;B3GALT5;ST8SIA1;FUT3 |
Metabolic pathways | DNMT3AA;UXS1;NDUFA6;P4HA2;CMAS;AMY1B;ASL;UPRT;ATP5J |
ST3GAL3 has several biochemical functions, for example, N-acetyllactosaminide alpha-2,3-sialyltransferase activity, beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST3GAL3 itself. We selected most functions ST3GAL3 had, and list some proteins which have the same functions with ST3GAL3. You can find most of the proteins on our site.
Function | Related Protein |
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N-acetyllactosaminide alpha-2,3-sialyltransferase activity | ST3GAL3A;ST3GAL3;ST3GAL3B |
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | ST3GAL1;ST3GAL5L;ST3GAL5;ST3GAL3;ST3GAL2L;ST3GAL4;ST3GAL2;ST3GAL3B;ST3GAL3A |
ST3GAL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST3GAL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST3GAL3.
ZBTB5; SCAMP2; TTR; RPL8; ACTG1
- Q&As
- Reviews
Q&As (6)
Ask a questionST3GAL3 proteins play an important role in the development of the nervous system, it is involved in the process of neuronal formation and synaptic connections, and is essential for the normal development and maintenance of the nervous system.
Yes, there are multiple subtypes of ST3GAL3 genes, which may have different functional and regulatory properties when encoding ST3GAL3 proteins.
The protein is a glycosyltransferase that participates in a glycosylation reaction that combines acetylneuraminic acid and sialic acid to form sialic acid-α-2,3-acetylneuraminominia. This glycosylation modification plays an important role in cell recognition and signaling.
ST3GAL3 protein has been linked to a variety of neurological-related diseases, including Parkinson's disease, Alzheimer's disease, Huntington's disease, and others. Abnormal expression or functional deficits may cause developmental and functional disorders of the nervous system.
There may be interactions between ST3GAL3 proteins and other molecules in the nervous system, such as with neuronal surface receptors or cell adhesion molecules, but the specific interaction network needs to be studied in depth.
ST3GAL3 proteins are involved in neuronal development by regulating signaling pathways related to cell adhesion, migration and synaptic formation, and the specific mechanism needs further study.
Customer Reviews (3)
Write a reviewThe catalytic activity of this protein is very excellent, and it can be widely used in various chemical reactions, so its application prospects are very broad.
Due to stability of ST3GAL3 is very strong, maintaining its structural and functional stability even after extensive use, which shows its excellent quality and reliability.
ST3GAL3 are very safe and can be used with confidence.
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