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ST6GAL1

  • Official Full Name

    ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

  • Overview

    This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
  • Synonyms

    ST6GAL1; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; sialyltransferase 1 (beta galactoside alpha 2,6 sialytransferase) , SIAT1; beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal I; alpha 2,6-ST 1; B-cell antigen CD75; Alpha2,6-(N)-Sialyltransferase; Alpha2,6-NST; 2,6-Sialyltransferase; α2, 6-sialyltransferase (C); alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In vitro E. coli expression system
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
  • 6×His, GFP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ST6GAL1-27H Active Recombinant Human ST6GAL1 Protein, His-tagged Mammalian cells His Glu44-Cys406
Human ST6GAL1-1122H Recombinant Human ST6GAL1, His tagged HEK293 His Lys 27 -Cys 406
Human ST6GAL1-58H Recombinant Human ST6GAL1 protein, His-tagged Insect Cell His
Human ST6GAL1-1919HCL Recombinant Human ST6GAL1 cell lysate Human Cell N/A
Human ST6GAL1-14H Active Recombinant Human ST6GAL1 Protein (AA 75-406), N-6×His/GFP tagged HEK293 N-6×His, GFP AA 75-406
Human ST6GAL1-11H Active Recombinant Human ST6GAL1 Protein (75-406), N-6×His and GFP tagged HEK293 N-6×His, GFP 75-406
Human ST6GAL1-2720H Recombinant Human ST6GAL1 Full Length Transmembrane protein (1-406 aa), His-tagged In vitro E. coli expression system His 1-406aa
Human ST6GAL1-4147H Recombinant Human ST6GAL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ST6GAL1-28H Active Recombinant Human ST6GAL1 Protein HEK293 27-406
Human ST6GAL1-6290H Recombinant Human ST6GAL1 Protein (Lys27-Cys406), C-His tagged Mammalian cells C-His Lys27-Cys406
Human ST6GAL1-2739H Recombinant Human ST6GAL1 Protein, His-tagged E.coli N-His Lys27-Cys406
Human ST6GAL1-4147H-B Recombinant Human ST6GAL1 Protein Pre-coupled Magnetic Beads HEK293
Human ST6GAL1-5097H Recombinant Human ST6GAL1 Protein (Lys27-Cys406), N-His tagged Mammalian cells N-His Lys27-Cys406
Mouse St6gal1-7036M Active Recombinant Mouse St6gal1, His tagged HEK293 His Lys 27-Cys 403
Mouse ST6GAL1-1760MCL Recombinant Mouse ST6GAL1 cell lysate Human Cell N/A
Rat ST6GAL1-961R Recombinant Rat ST6GAL1 Protein (Lys27-Cys403), His-tagged HEK293 His Lys27-Cys403
Homo sapiens (Human) RFL34414HF Recombinant Full Length Human Beta-Galactoside Alpha-2,6-Sialyltransferase 1(St6Gal1) Protein, His-Tagged E.coli expression system His Full Length (1-406aa)
Rattus norvegicus (Rat) RFL6513RF Recombinant Full Length Rat Beta-Galactoside Alpha-2,6-Sialyltransferase 1(St6Gal1) Protein, His-Tagged E.coli expression system His Full Length (1-403)
Rhesus Macaque ST6GAL1-4501R Recombinant Rhesus monkey ST6GAL1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ST6GAL1-4317R-B Recombinant Rhesus Macaque ST6GAL1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ST6GAL1-4317R Recombinant Rhesus Macaque ST6GAL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ST6GAL1-1140Z Recombinant Zebrafish ST6GAL1 Mammalian Cell His
Chicken ST6GAL1-6794C Recombinant Chicken ST6GAL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ST6GAL1 Related Research Area

ST6GAL1 involved in several pathways and played different roles in them. We selected most pathways ST6GAL1 participated on our site, such as N-Glycan biosynthesis, Other types of O-glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST6GAL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
N-Glycan biosynthesisMGAT4B;MAN1B1;ALG10;ALG8;MGAT1;TUSC3;MOGS;RPN2;DPM2
Other types of O-glycan biosynthesisPOFUT2;PLOD3;B3GAT2;ST6GAL2A;MFNG;FUT7;OGT.1;POMT2;COLGALT2
Metabolic pathwaysATP6V0A1;POLD2;AK4;TYMP;ADKA;DNMT3;GAD1B;MOGAT3;INPP5L

ST6GAL1 has several biochemical functions, for example, beta-galactoside alpha-2,6-sialyltransferase activity, protein binding, sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST6GAL1 itself. We selected most functions ST6GAL1 had, and list some proteins which have the same functions with ST6GAL1. You can find most of the proteins on our site.

Function Related Protein
beta-galactoside alpha-2,6-sialyltransferase activityST6GAL2A;ST6GAL2;ST6GAL2B;ST6GAL1
protein bindingEPM2A;HHIP;RAD23A;AEBP2;KRTAP12-2;ARPIN;TRIB3;TMEM19;MFAP1
sialyltransferase activityST8SIA1;ST6GALNAC5;ST6GALNAC2;ST6GALNAC3;ST3GAL2L;ST6GAL1;ST3GAL5;ST3GAL5L;ST6GALNAC6

ST6GAL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST6GAL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST6GAL1.

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  • Q&As
  • Reviews

Q&As (6)

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Is ST6GAL1 involved in cell signaling by interacting with receptors? 10/18/2019

This proteins regulate cell signaling by interacting with a variety of protein receptors, and the specific mechanism needs to be further studied.

What factors regulate ST6GAL1 protein expression? 08/17/2019

The expression of ST6GAL1 proteins is affected by many factors, including cell differentiation, inflammation, viral infection, etc.

What is the role of ST6GAL1 in diabetes? 06/24/2019

Involved in the insulin signaling pathway in diabetes, studies have shown that it can influence insulin signaling, which in turn affects blood sugar levels.

In which biological processes does ST6GAL1 play an important role? 06/13/2019

Plays an important role in a variety of biological processes, such as cell differentiation, glycoprotein modification, cell-cell interactions, etc.

Are ST6GAL1 involved in the cancer process? 03/20/2019

ST6GAL1 plays an increasingly important role in cancer processes, regulating the invasion and metastasis of cancer cells, and studies have found that it is involved in many cancer processes.

What cell signaling pathways are ST6GAL1 proteins involved in? 01/22/2019

ST6GAL1 proteins participate in the regulation of various cell signaling pathways, such as inflammatory signaling pathways, insulin signaling pathways, stem cell signaling pathways, etc.

Customer Reviews (3)

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Reviews
04/26/2022

    This reproducibility of ST6GAL1 is very good, and it can maintain a high degree of consistent performance regardless of the conditions, making it ideal for experiments or applications that require a high degree of reproducibility.

    04/15/2021

      Production process of ST6GAL1 focuses on resource recycling, reusing waste and reducing the consumption of natural resources.

      02/03/2021

        The catalytic activity of this protein is very strong, it can perform excellent catalysis even under extremely harsh conditions, and its stability is impressive.

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