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ST6GALNAC6

Official Full Name

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Overview

ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter;cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 (PubMed 12668675)).
Synonyms

ST6GALNAC6; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; sialytransferase 7 ((alpha N acetylneuraminyl 2,3 betagalactosyl 1,3) N acetyl galactosaminide alpha 2,6 sialytransferase) F , SIAT7F; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GALNACVI; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 6; CMP NeuAC:(beta) N acetylgalactosaminide (alpha)2 6 sialyltransferase member VI; GalNAc alpha 2 6 sialyltransferase VI; hST6GalNAc VI; RP11 203J24.3; Sialyltransferase 7F; Sialyltransferase7F; Sialytransferase 7 ((alpha N acetylneuraminyl 2 3 betagalactosyl 1 3) N acetyl galactosaminide alpha 2 6 sialytransferase) F; SIAT 7F; SIAT7F; ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 6; ST6GalNAc VI; SIAT7-F; galNAc alpha-2,6-sialyltransferase VI; CMP-NeuAC:(beta)-N-acetylgalactosaminide (alpha)2,6-sialyltransferase member VI; sialytransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialytransferase) F; RP11-203J24.3;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ST6GALNAC6-2980H	Recombinant Human ST6GALNAC6, GST-tagged	E.coli	GST	67-333aa	$319 / 25ug
Human	ST6GALNAC6-1704HCL	Recombinant Human ST6GALNAC6 cell lysate		N/A		Inquiry
Human	ST6GALNAC6-3501H	Recombinant Human ST6GALNAC6 Protein (Val67-Thr333), His tagged	E.coli	His	Val67-Thr333	Inquiry
Human	ST6GALNAC6-18H	Recombinant Human ST6GALNAC6 Protein (AA 33-333), N-6×His/GFP tagged	HEK293	N-6×His, GFP	AA 33-333	Inquiry

Involved Pathway
Protein Function
Interacting Protein
ST6GALNAC6 Related Articles

ST6GALNAC6 involved in several pathways and played different roles in them. We selected most pathways ST6GALNAC6 participated on our site, such as Glycosphingolipid biosynthesis - ganglio series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST6GALNAC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycosphingolipid biosynthesis - ganglio series	HEXB;ST6GALNAC4;SLC33A1;GLB1;ST8SIA1;ST3GAL2;ST3GAL1;ST6GALNAC3;ST6GALNAC5
Metabolic pathways	ACSL4B;PNAT10;ACAA1;CYP21A1;PIP5K1A;ALDOA;PDHB;BCMO1;PIK3C2B

ST6GALNAC6 has several biochemical functions, for example, alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity, sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST6GALNAC6 itself. We selected most functions ST6GALNAC6 had, and list some proteins which have the same functions with ST6GALNAC6. You can find most of the proteins on our site.

Function	Related Protein
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	ST6GALNAC5B;ST6GALNAC1.2;ST6GALNAC1;ST6GALNAC4;ST6GALNAC5;ST6GALNAC3;ST6GALNAC6
sialyltransferase activity	ST6GAL2B;ST6GALNAC5;ST6GALNAC4;ST3GAL2L;ST6GAL1;ST6GALNAC2;ST3GAL5L;ST6GALNAC3;ST6GALNAC1.2

ST6GALNAC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST6GALNAC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST6GALNAC6.

ATXN1; MYC

Kroes, RA; He, HA; et al. Overexpression of ST6GalNAcV, a ganglioside-specific alpha 2,6-sialyltransferase, inhibits glioma growth in vivo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107:12646-12651(2010).