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STAG1

Official Full Name

stromal antigen 1
Overview

This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.
Synonyms

STAG1; stromal antigen 1; cohesin subunit SA-1; SA 1; SCC3A; SCC3 homolog 1; nuclear protein stromal antigen 1; SA1; DKFZp781D1416;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	STAG1-2986H	Recombinant Human STAG1, GST-tagged	E.coli	GST	880-1221aa	$319 / 25ug
Human	STAG1-29260TH	Recombinant Human STAG1, His-tagged	E.coli	His		Inquiry
Human	STAG1-1430HCL	Recombinant Human STAG1 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	STAG1-16089M	Recombinant Mouse STAG1 Protein	Mammalian Cell	His		Inquiry
Mouse	STAG1-8771M	Recombinant Mouse STAG1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	STAG1-8771M-B	Recombinant Mouse STAG1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

STAG1 involved in several pathways and played different roles in them. We selected most pathways STAG1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	HAUS2;CHEK1;CEP76;CSNK2B;FZR1;RCC2;GADD45BA;RBBP8;CDC25B
Cell Cycle, Mitotic	CDK11A;CCDC99;CDKN2B;LIN9;SMC4;SSNA1;NCAPH2;NUPL2;ESCO1
Cohesin Loading onto Chromatin	WAPAL;PDS5A;NIPBLB;NIPBLA;STAG2;MAU2;STAG1;NIPBL;PDS5B
Establishment of Sister Chromatid Cohesion	PDS5B;PDS5A;ESCO2;CDCA5;WAPAL;STAG2;STAG1;ESCO1
M Phase	SGOL1;KIF2A;GORASP1;MLF1IP;SPC25;NEK7;NIPBL;SKA2;CENPN
Meiosis	SYNE1;PSMC3IP;TERF2IP;TEX15;TINF2;TERF1;TEX12;POT1;FKBP6
Meiotic synapsis	SYCP1;SYNE2;TERF2IP;TERF2;STAG1;POT1A;SUN2;SYCE2;TINF2

STAG1 has several biochemical functions, for example, chromatin binding, protein binding, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STAG1 itself. We selected most functions STAG1 had, and list some proteins which have the same functions with STAG1. You can find most of the proteins on our site.

Function	Related Protein
chromatin binding	ERG;MITF;C19orf40;POU2F1;ANKRD17;HMGB1;DLX2;HMG20B;ATF2
protein binding	RBL2;PYGL;SLX4;CTF1;CCT8;SLC19A2;AHSP;SELE;ANKS4B
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	MSGN1;BARHL1A;FOXC1;FOXF1;PPARG;NKX2-5;MAF;ELF5;ONECUT3

STAG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STAG1.

SMC3; RAD21; WAPAL