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STAR

  • Official Full Name

    steroidogenic acute regulatory protein

  • Overview

    The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the;conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by;mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane.;Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A;pseudogene of this gene is located on chromosome 13.
  • Synonyms

    STAR; steroidogenic acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein, mitochondrial; StAR related lipid transfer (START) domain containing 1; STARD1; mitochondrial; Cholesterol trafficker; Luteinizing hormone induced protein; Luteinizing hormone-induced protein; Mitochondrial steroid acute regulatory protein; STAR_HUMAN; START domain containing protein 1; START domain-containing protein 1; Steroidogenic acute regulatory protein mitochondrial; OTTHUMP00000225718; OTTHUMP00000225719; OTTHUMP00000225878; START domain containing 1; steroid acute regulatory protein; START domain-containing protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human STAR-30115TH Recombinant Human STAR Wheat Germ N/A 286 amino acids
Human STAR-30116TH Recombinant Human STAR, His-tagged E.coli His 222 amino acids
Human STAR-1292H Recombinant Human Steroidogenic Acute Regulatory Protein, His-tagged Human His
Human STAR-637HCL Recombinant Human STAR lysate HEK293 N/A
Human STAR-507H Recombinant Human STAR Protein, His/GST-tagged E.coli His/GST Met1~Cys285
Human STAR-1693HFL Recombinant Full Length Human STAR Protein, C-Flag-tagged Mammalian cells Flag
Human STAR-2903H Recombinant Human STAR Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human STAR-1396H Recombinant Human STAR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human STAR-6200H Recombinant Human STAR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human STAR-6358H Recombinant Human STAR Protein (Met1-Cys285), N-GST tagged E.coli N-GST Met1-Cys285
Human STAR-2113H-B Recombinant Human STAR Protein Pre-coupled Magnetic Beads HEK293
Human STAR-504HF Recombinant Full Length Human STAR Protein In Vitro Cell Free System 286 amino acids
Human STAR-2113H Recombinant Human STAR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse STAR-16098M Recombinant Mouse STAR Protein Mammalian Cell His
Mouse STAR-8780M-B Recombinant Mouse STAR Protein Pre-coupled Magnetic Beads HEK293
Mouse Star-6162M Recombinant Mouse Star Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse STAR-8780M Recombinant Mouse STAR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat STAR-5777R Recombinant Rat STAR Protein Mammalian Cell His
Rat STAR-5436R Recombinant Rat STAR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat STAR-5436R-B Recombinant Rat STAR Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque STAR-4510R Recombinant Rhesus monkey STAR Protein, His-tagged Mammalian Cell His
Rhesus Macaque STAR-4326R-B Recombinant Rhesus Macaque STAR Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque STAR-4326R Recombinant Rhesus Macaque STAR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish STAR-9193Z Recombinant Zebrafish STAR Mammalian Cell His
Chicken STAR-6252C Recombinant Chicken STAR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • STAR Related Articles

STAR involved in several pathways and played different roles in them. We selected most pathways STAR participated on our site, such as Ovarian steroidogenesis, Aldosterone synthesis and secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ovarian steroidogenesisHSD3B2;HSD17B1;INSR;INS;LHCGR;LHB;HSD17B7;INS2;IGF1R
Aldosterone synthesis and secretionPRKCA;PRKCG;ITPR3;GNAQ;STAR;PLCB2;NETO2;CAMK2A;Adcy4

STAR has several biochemical functions, for example, cholesterol binding, cholesterol transporter activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STAR itself. We selected most functions STAR had, and list some proteins which have the same functions with STAR. You can find most of the proteins on our site.

Function Related Protein
cholesterol bindingPMP2;APOA1A;CYP11A1;NR1H3;APOE;STARD6;OSBPL10;OSBPL8;APOEB
cholesterol transporter activityABCA1B;ABCA7;CETP;ABCA13;APOA4B.2;ABCA1;APOA4B.1;APOA4;APOA1
protein bindingCD151;FAM46B;SALL2;ANKS1A;KCNJ5;SHC4;PPP3CB;C16orf48;MEA1

STAR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAR here. Most of them are supplied by our site. Hope this information will be useful for your research of STAR.

MAGEA11; CCHCR1; FEZ1

Kahveci, MU; Ciftci, M; et al. Photoinduced in situ formation of clickable PEG hydrogels and their antibody conjugation. DESIGNED MONOMERS AND POLYMERS 18:129-136(2015).
Accialini, P; Hernandez, SF; et al. A link between Notch and progesterone maintains the functionality of the rat corpus luteum. REPRODUCTION 149:1-10(2015).
  • Q&As
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