STAT5A
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Official Full Name
STAT5A signal transducer and activator of transcription 5A
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Synonyms
STAT5A; signal transducer and activator of transcription 5A; STAT5; MGF;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human cells
- Mammalian Cell
- Mammalian cells
- Sf9 Insect Cell
- DYKDDDDK
- Flag
- His
- His (Fc)
- Avi
- His|MBP
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- STAT5A Related Gene Family
- STAT5A Related Signal Pathway
STAT5A involved in several pathways and played different roles in them. We selected most pathways STAT5A participated on our site, such as ErbB signaling pathway, Jak-STAT signaling pathway, Prolactin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAT5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ErbB signaling pathway | PRKCBB;PIK3R3B;SHC4;NCK2B;GSK3B;PAK2A;MAPK8;MAPK8B;PAK6 |
Jak-STAT signaling pathway | SOCS3B;IFNAR2;GHR;RAF1;IL15RA;MYCB;HRASB;STAT5A;PIK3R5 |
Prolactin signaling pathway | CSH;SHC2;PIK3R2;CCND1;SHC4;MAPK8;PRLR;MAPK1;STAT5B |
Hepatitis B | NFATC1;CCNE1;NFATC4;CASP10;AKT2;PIK3CA;NFATC2;TGFB2;APAF1 |
Measles | STAT3;MAVS;PIK3CB;CCNE1;PIK3CD;CBLB;CD3G;HSPA6;AKT2 |
HTLV-I infection | RRAS;TGFBR2;RAN;TP53;CD40;TGFB2;HLA-DPA1;AKT2;RRAS2 |
Pathways in cancer | PTGER2;TRAF3;TCF7L2;CUL2;WNT3A;GLI1;CDC42;MMP9;MECOM |
Viral carcinogenesis | POLB;HDAC9;BAX;RBL2;GTF2H2;Casp3;HIST2H4A;SRC;PIK3CA |
Chronic myeloid leukemia | PIK3R3;IKBKG;NFKB1;MAPK3;SHC1;CBLC;PTPN11;TGFBR2;SHC2 |
Acute myeloid leukemia | TCF7;HRAS;FLT3;RUNX1;RUNX1T1;TCF7L2;PIK3CA;SPI1;CEBPA |
STAT5A has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by STAT5A itself. We selected most functions STAT5A had, and list some proteins which have the same functions with STAT5A. You can find most of the proteins on our site.
Function | Related Protein |
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RNA polymerase II core promoter sequence-specific DNA binding | PAX6;MAZ;GBX2;RUVBL2;H2AFZ;RUNX2;NR4A2;ZNF277;TAL1 |
protein binding | ERCC8;ANKS4B;ACTB;ARPC5;DCPS;UXT;ZNF131;RFC5;APOO |
signal transducer activity | PTGER4B;PLCH2;STAT3;TMTOPS2A;OLFR13;OLFR482;TRIM63;GRM2A;OLFR469 |
transcription factor activity, sequence-specific DNA binding | FOXM1;TAF5L;IRF1B;RELB;ZNF167;ZFP27;ZNF792;SPZ1;TEAD1 |
STAT5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAT5A here. Most of them are supplied by our site. Hope this information will be useful for your research of STAT5A.
PTPN1; TCF12; AGAP2; STAP2; il2ra_human_gene
- Q&As
- Reviews
Q&As (5)
Ask a questionSTAT5A plays a crucial role in regulating immune responses by influencing the differentiation and function of immune cells such as T cells and natural killer cells.
Yes, several clinical trials are exploring the therapeutic potential of targeting STAT5A in different cancer types.
One challenge is the need for specificity in targeting STAT5A to avoid adverse effects on normal cellular functions.
Elevated levels of activated STAT5A have been correlated with poor prognosis in certain cancers, suggesting its potential as a prognostic marker.
Dysregulations of STAT5A have been linked to leukemia, breast cancer, and prostate cancer, among other diseases.
Customer Reviews (3)
Write a reviewThe manufacturer offers exceptional technical assistance, guiding researchers through various stages of their experiments.
Its reliable bioactivity makes it an ideal choice for a diverse range of experimental applications.
By providing comprehensive data and resources, the manufacturer enables researchers to design and implement their trials with confidence, ensuring the desired outcomes.
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