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GLRA1

  • Official Full Name

    glycine receptor, alpha 1

  • Overview

    The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates;postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE),;also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different;isoforms have been found for this gene.
  • Synonyms

    GLRA1; glycine receptor, alpha 1; glycine receptor, alpha 1 (startle disease/hyperekplexia) , STHE; glycine receptor subunit alpha-1; startle disease/hyperekplexia; stiff person syndrome; glycine receptor 48 kDa subunit; glycine receptor strychnine-bindin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GLRA1-27289TH Recombinant Human GLRA1 Wheat Germ N/A 100 amino acids
Human GLRA1-13307H Recombinant Human GLRA1, GST-tagged E.coli GST 27-250a.a.
Human GLRA1-712HCL Recombinant Human GLRA1 cell lysate N/A
Human GLRA1-4970H Recombinant Human GLRA1 Protein, GST-tagged Wheat Germ GST
Human GLRA1-5343HF Recombinant Full Length Human GLRA1 Protein, GST-tagged In Vitro Cell Free System GST 449 amino acids
Rat GLRA1-2567R Recombinant Rat GLRA1 Protein Mammalian Cell His
Rat GLRA1-2222R Recombinant Rat GLRA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GLRA1-2222R-B Recombinant Rat GLRA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GLRA1-1871R Recombinant Rhesus monkey GLRA1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GLRA1-1691R-B Recombinant Rhesus Macaque GLRA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GLRA1-1691R Recombinant Rhesus Macaque GLRA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GLRA1-8975Z Recombinant Zebrafish GLRA1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GLRA1 involved in several pathways and played different roles in them. We selected most pathways GLRA1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionPRLRA;ADRA1BB;TAAR64;P2RX2;LEPR;GABRR2;TRY;TAAR4;CHRM2A

GLRA1 has several biochemical functions, for example, extracellular-glycine-gated chloride channel activity, contributes_to extracellular-glycine-gated chloride channel activity, glycine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRA1 itself. We selected most functions GLRA1 had, and list some proteins which have the same functions with GLRA1. You can find most of the proteins on our site.

Function Related Protein
extracellular-glycine-gated chloride channel activityGLRA4A;GLRA1;GLRBA;GLRB;GLRBB;GLRA2;SIX2A
contributes_to extracellular-glycine-gated chloride channel activityGLRA3;GLRA4B;GLRA1;GLRB;GLRBA
glycine bindingSIX2A;GLDC;SRR;ALAS2;GRIN2B;GNMT;GRIN1;GRIN3A;GSS
protein bindingALG2;FSTL3;PRAM1;UBB;TJP2;STAT2;UQCC2;CNOT8;CAMKK1
taurine bindingGLRA1;SLC6A6
transmitter-gated ion channel activityGLRA2;SIX2A;GLRA4B;GLRA4A;GLRA3;GLRA1

GLRA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLRA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLRA1.

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