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STIM1

  • Official Full Name

    stromal interaction molecule 1

  • Overview

    Ca2+ is a key second messenger in many intracellular signaling pathways. Ca2+ signals control many cellular functions ranging from short-term responses such as contraction and secretion to longer-term regulation of cell growth and proliferation. Stromal i
  • Synonyms

    STIM1; stromal interaction molecule 1; D11S4896E; GOK; STIM1L;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • CaM
  • C
  • His
  • Flag
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human STIM1-8132H Recombinant Human STIM1 protein, His & T7-tagged E.coli His/T7 Met1~Leu211 (Accession # Q13586)
Human STIM1-344H Recombinant Human Stromal Interaction Molecule 1, CaM-tagged E.coli CaM
Human STIM1-3208H Recombinant Human STIM1, His tagged Human Cell His
Human STIM1-4619H Recombinant Stromal Interaction Molecule 1 Human N/A
Human STIM1-2277HCL Recombinant Human STIM1 cell lysate Human Cell N/A
Human STIM1-6371H Recombinant Human STIM1 Protein (Ser28-Leu211), N-His tagged E.coli N-His Ser28-Leu211
Human STIM1-2883H Recombinant Human STIM1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human STIM1-0415H Recombinant Human STIM1 protein, His-tagged E.coli His 2-350 aa
Human STIM1-1088HFL Recombinant Full Length Human STIM1 Protein, C-Flag-tagged Mammalian cells Flag
Human STIM1-2121H-B Recombinant Human STIM1 Protein Pre-coupled Magnetic Beads HEK293
Human STIM1-2121H Recombinant Human STIM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human STIM1-2857H Recombinant Human STIM1 protein(251-420 aa), C-His-tagged E. coli C-His 251-420 aa
Human STIM1-2858H Recombinant Human STIM1 protein(31-210 aa), C-His-tagged E. coli C-His 31-210 aa
Mouse STIM1-16128M Recombinant Mouse STIM1 Protein Mammalian Cell His
Mouse STIM1-8799M-B Recombinant Mouse STIM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Stim1-6179M Recombinant Mouse Stim1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse STIM1-8799M Recombinant Mouse STIM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat STIM1-5788R Recombinant Rat STIM1 Protein Mammalian Cell His
Rat STIM1-5447R-B Recombinant Rat STIM1 Protein Pre-coupled Magnetic Beads HEK293
Rat STIM1-5447R Recombinant Rat STIM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rattus norvegicus (Rat) RFL23771RF Recombinant Full Length Rat Stromal Interaction Molecule 1(Stim1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-685)
Rhesus Macaque STIM1-4523R Recombinant Rhesus monkey STIM1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque STIM1-4339R Recombinant Rhesus Macaque STIM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque STIM1-4339R-B Recombinant Rhesus Macaque STIM1 Protein Pre-coupled Magnetic Beads HEK293
Chicken STIM1-2534C Recombinant Chicken STIM1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • STIM1 Related Articles
  • STIM1 Related Research Area

STIM1 involved in several pathways and played different roles in them. We selected most pathways STIM1 participated on our site, such as Calcium signaling pathway, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with STIM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayDRD1B;CACNA1G;ITPKB;GNA15.1;ORAI2;CAMK2D2;PPP3CA;GNA15;ATP2B3B
Platelet activationARHGAP35;PRKACB;Adcy4;ROCK1;F2RL3;NOS3;PLCB1;ITGB1;TLN1

STIM1 has several biochemical functions, for example, calcium channel regulator activity, calcium ion binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STIM1 itself. We selected most functions STIM1 had, and list some proteins which have the same functions with STIM1. You can find most of the proteins on our site.

Function Related Protein
calcium channel regulator activityHPCAL4;GRM7;STIM1A;PRKCB;CACNA2D2;PLN;SGK2B;GRM6A;SGK1
calcium ion bindingCDH12;FSTL4;PCDH2G10;PCDH2AA3;EFCAB6;SDF4;ITIH1;FLG2;KCNIP4
identical protein bindingFHOD1;TNF;CASC3;LYZ;STAT6;SERPINA1A;ALCAMB;CLDN17;MRI1
microtubule plus-end bindingKIF2C;STIM1;CLASP1A;KIF18A;MAPRE1;APC;CLIP2;CLASP1;DST
protease bindingFURIN;DERL1;BCL10;TIMP3;SERPINB6;ITGAV;NDUFS7;TIMP2A;INS2
protein bindingLCE4A;C17orf82;CITED2;TNFSF13B;SYCE3;UBE2U;WFDC9;CARD11;NMI

STIM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STIM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STIM1.

ORAI1

Gaida, K; Salimi-Moosavi, H; et al. Inhibition of CRAC with a human anti-ORAI1 monoclonal antibody inhibits T-cell-derived cytokine production but fails to inhibit a T-cell-dependent antibody response in the cynomolgus monkey. JOURNAL OF IMMUNOTOXICOLOGY 12:164-173(2015).
Saliba, Y; Keck, M; et al. Emergence of Orai3 activity during cardiac hypertrophy. CARDIOVASCULAR RESEARCH 105:248-259(2015).
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