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STX2

Official Full Name

syntaxin 2
Overview

The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms

STX2; syntaxin 2; EPIM, epimorphin , STX2A, STX2B, STX2C; syntaxin-2; EPM; EPIM; Epimorphin; MGC51014; OTTHUMP00000238636; OTTHUMP00000238637; STX2_HUMAN; STX2A; STX2B; STX2C; Syntaxin 2C;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Homo sapiens (Human)
Human
Mouse
Rat
Rattus norvegicus (Rat)

Source

E.coli
E.coli expression system
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
MYC
Myc|DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	STX2-4046H	Recombinant Human STX2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	STX2-30658TH	Recombinant Human STX2	Wheat Germ	N/A	287 amino acids	Inquiry
Human	STX2-6854H	Recombinant Human Syntaxin 2, His-tagged	E.coli	His	1-264aa	Inquiry
Human	STX2-1718HCL	Recombinant Human STX2 cell lysate		N/A		Inquiry
Human	STX2-1546H	Recombinant Human STX2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	STX2-5749H	Recombinant Human STX2 Protein (Met1-Arg188), N-His tagged	E.coli	N-His	Met1-Arg188	Inquiry
Human	STX2-4748HF	Recombinant Full Length Human STX2 Protein, GST-tagged	In Vitro Cell Free System	GST	287 amino acids	Inquiry
Human	STX2-2990H	Recombinant Human STX2 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	STX2-512HF	Recombinant Full Length Human STX2 Protein	In Vitro Cell Free System		287 amino acids	Inquiry
Mouse	Stx2-411M	Active Recombinant Mouse Syntaxin 2	E.coli	N/A		Inquiry
Mouse	Stx2-961M	Recombinant Mouse Stx2 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Rat	STX2-5813R	Recombinant Rat STX2 Protein	Mammalian Cell	His		Inquiry
Rat	STX2-5472R-B	Recombinant Rat STX2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	STX2-5472R	Recombinant Rat STX2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Homo sapiens (Human)	RFL15805HF	Recombinant Full Length Human Syntaxin-2(Stx2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-288)	Inquiry
Rattus norvegicus (Rat)	RFL20799RF	Recombinant Full Length Rat Syntaxin-2(Stx2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-290)	Inquiry
Chicken	STX2-3547C	Recombinant Chicken STX2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
STX2 Related Articles
STX2 Related Research Area

STX2 involved in several pathways and played different roles in them. We selected most pathways STX2 participated on our site, such as SNARE interactions in vesicular transport, Synaptic vesicle cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
SNARE interactions in vesicular transport	VAMP8;STX1A;STX5A;STX3A;STX8;STX4;BET1L;VTI1B;SEC22B
Synaptic vesicle cycle	VAMP2;STX3;ATP6V1E2;SLC18A2;ATP6V1G1;SNAP25;UNC13C;UNC13A;ATP6V1C2

STX2 has several biochemical functions, for example, SNAP receptor activity, SNARE binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX2 itself. We selected most functions STX2 had, and list some proteins which have the same functions with STX2. You can find most of the proteins on our site.

Function	Related Protein
SNAP receptor activity	SEC22A;SNAP23.1;STX1A;VTI1B;STX5;SNAP29;SYBL1;SNAP25B;STX18
SNARE binding	VAMP4;GABARAPL2;STX11B.2;VAMP3;STX5AL;EXOC3;GOSR1;VAMP2;VTI1A
calcium-dependent protein binding	TNNC1;STMN2;SNAP25;CD209A;NRXN1;CALM3;ANXA1;CHP1;CLEC4M
protein binding	CCDC112;RAB14;C1orf50;CARD8;ACTN4;NIPA2;SLC19A2;DISC1;PSMF1
protein dimerization activity	ATOH8;HER11;NEUROD6B;GRIN2A;CLOCK;ATOH1B;DBI;HNF1A;SRFA

STX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX2.

VAMP3

Diodati, ME; Bates, AH; et al. High Genotypic and Phenotypic Similarity Among Shiga Toxin-Producing Escherichia coli O111 Environmental and Outbreak Strains. FOODBORNE PATHOGENS AND DISEASE 12:235-243(2015).

Arimitsu, H; Sasaki, K; et al. Isolation of B subunit-specific monoclonal antibody clones that strongly neutralize the toxicity of Shiga toxin 2. MICROBIOLOGY AND IMMUNOLOGY 59:71-81(2015).

Synaptic SNAREs