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STXBP1

  • Official Full Name

    syntaxin binding protein 1

  • Overview

    This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of;neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have;been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been;described.
  • Synonyms

    STXBP1; syntaxin binding protein 1; syntaxin-binding protein 1; hUNC18; MUNC18 1; rbSec1; UNC18; N-Sec1; unc-18A; unc18-1; neuronal SEC1; protein unc-18 homolog 1; protein unc-18 homolog A; P67; NSEC1; MUNC18-1; FLJ37475;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • terminal 6xHis
  • MBP
  • tagged
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human STXBP1-28545TH Recombinant Human STXBP1 Wheat Germ N/A 95 amino acids
Human STXBP1-3924H Recombinant Human STXBP1 protein, His&GST-tagged Insect Cells His/GST Met1-Ser594
Human STXBP1-3034H Recombinant Human STXBP1, GST-tagged E.coli GST C-term-350aa
Human STXBP1-624HCL Recombinant Human STXBP1 cell lysate Insect Cell N/A
Human STXBP1-3600H Recombinant Human STXBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human STXBP1-2987H Recombinant Human STXBP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human STXBP1-4582H Recombinant Human STXBP1 protein E.coli N/A 1-594aa
Human STXBP1-5067H Recombinant Human STXBP1 protein, His-tagged HEK293 His 1-594aa
Human STXBP1-2135H Recombinant Human STXBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human STXBP1-2135H-B Recombinant Human STXBP1 Protein Pre-coupled Magnetic Beads HEK293
Human STXBP1-3540H Recombinant Human STXBP1 protein, N-terminal 6xHis-MBP-tagged-tagged E.coli N-terminal 6xHis-MBP-tagged 1-594aa
Human STXBP1-457HFL Recombinant Full Length Human STXBP1 Protein, C-Flag-tagged Mammalian cells Flag
Mouse STXBP1-16196M Recombinant Mouse STXBP1 Protein Mammalian Cell His
Mouse STXBP1-8844M Recombinant Mouse STXBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Stxbp1-6209M Recombinant Mouse Stxbp1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse STXBP1-8844M-B Recombinant Mouse STXBP1 Protein Pre-coupled Magnetic Beads HEK293
Rat STXBP1-5819R Recombinant Rat STXBP1 Protein Mammalian Cell His
Rat STXBP1-5478R Recombinant Rat STXBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat STXBP1-5478R-B Recombinant Rat STXBP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque STXBP1-4551R Recombinant Rhesus monkey STXBP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque STXBP1-4367R Recombinant Rhesus Macaque STXBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque STXBP1-4367R-B Recombinant Rhesus Macaque STXBP1 Protein Pre-coupled Magnetic Beads HEK293
Chicken STXBP1-7099C Recombinant Chicken STXBP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • STXBP1 Related Articles
  • STXBP1 Related Research Area

STXBP1 involved in several pathways and played different roles in them. We selected most pathways STXBP1 participated on our site, such as Synaptic vesicle cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with STXBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Synaptic vesicle cycleATP6V0B;NSF;ATP6V1C2;ATP6V1D;ATP6V1C1;SLC17A6;ATP6V1E2;STX2;STX1A

STXBP1 has several biochemical functions, for example, SNARE binding, identical protein binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STXBP1 itself. We selected most functions STXBP1 had, and list some proteins which have the same functions with STXBP1. You can find most of the proteins on our site.

Function Related Protein
SNARE bindingSTX7;STX3A;SYT1;STX4;ANKRD27;EXOC3;GABARAPL2;EXOC3L4;SNAPIN
identical protein bindingMVK;CLDN20;ABCD1;ERBB3;BNIP2;CCDC109A;SID4;PITX2;AIM2
poly(A) RNA bindingTHOC4;PTRF;HIST1H1E;SF3A3;CRNKL1;DHX36;SEC61B;CCDC137;EIF1
protein N-terminus bindingHDAC1;ACOX1;SDCBP;SMARCE1;ARF6;TGFB1;SLC6A3;ZWINT;ACTN4
protein bindingPTPN12;ZNF664-FAM101A;LMAN1;PHF17;ARPIN;EMID2;POR;EPC1;FAT4
protein domain specific bindingTJP1;ARL1;CENPJ;ICA1L;NDE1;DVL2;MITD1;YWHABL;ACSL3
protein kinase bindingTRIM5;AURKA;ADAM10;Fert2;FAM83A;CDKN2C;FAM83E;AP2A2;RPS6
syntaxin bindingSYT7B;CPLX4B;PTPN2;SYTL2;CPLX2;SYT11B;SYT5B;STX16;SYT6
syntaxin-1 bindingSLC6A4;GOLSYN;LRRK2;CCDC167;CPLX1;SNAP25A;RNF40;SYBU;STXBP2

STXBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STXBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STXBP1.

TRIM38; STX11; STX19; PRKAR1A; PLD1; APP; ID1; HTT; Plk2; IQCB1; FERMT3; Phospho1; Sart3; DNAJC11

Rodriguez, AR; Muller, LPD; et al. The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina. JOURNAL OF COMPARATIVE NEUROLOGY 522:1411-1443(2014).
Ramakrishnan, NA; Drescher, MJ; et al. Calcium Regulates Molecular Interactions of Otoferlin with Soluble NSF Attachment Protein Receptor ( SNARE) Proteins Required for Hair Cell Exocytosis*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:8750-8766(2014).
  • Q&As
  • Reviews

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Customer Reviews (3)

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Reviews
02/02/2023

    Considering its outstanding performance across multiple assays, I confidently endorse the inclusion of the STXBP1 protein in diverse research studies.

    12/25/2020

      I highly recommend the use of the STXBP1 protein in various experimental applications.

      05/08/2019

        The STXBP1 protein has been successfully utilized in protein electron microscopy structure analysis, providing valuable insights into molecular structures and interactions.

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