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SUCLG2

  • Official Full Name

    succinate-CoA ligase, GDP-forming, beta subunit

  • Overview

    This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12.
  • Synonyms

    SUCLG2; succinate-CoA ligase, GDP-forming, beta subunit; succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial; EC 6.2.1.4; G BETA; GBETA; GTP specific succinyl-CoA synthetase beta subunit; GTP specific succinyl-CoA synthetase subunit beta; SCS betaG; Succinate CoA ligase GDP forming beta subunit; Succinate-Coenzyme A ligase, GDP-forming, beta subunit; Succinyl CoA ligase GDP forming beta chain mitochondrial; Succinyl CoA synthetase betaG chain; Succinyl-CoA synthetase beta-G chain; SCS-betaG; OTTHUMP00000213363; OTTHUMP00000213364; OTTHUMP00000213365; succinyl-CoA synthetase, beta-G chain; GTP-specific succinyl-CoA synthetase beta subunit; GTP-specific succinyl-CoA synthetase subunit beta; succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SUCLG2-3043H Recombinant Human SUCLG2, His-tagged E.coli His C-term-384aa
Human SUCLG2-1365HCL Recombinant Human SUCLG2 293 Cell Lysate HEK293 N/A
Human SUCLG2-3044H Recombinant Human SUCLG2 protein, His-SUMO-tagged E.coli His-SUMO 49-423aa
Mouse SUCLG2-16209M Recombinant Mouse SUCLG2 Protein Mammalian Cell His
Mouse SUCLG2-8853M Recombinant Mouse SUCLG2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SUCLG2-8853M-B Recombinant Mouse SUCLG2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SUCLG2-4555R Recombinant Rhesus monkey SUCLG2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SUCLG2-4371R Recombinant Rhesus Macaque SUCLG2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SUCLG2-4371R-B Recombinant Rhesus Macaque SUCLG2 Protein Pre-coupled Magnetic Beads HEK293
Chicken SUCLG2-1293C Recombinant Chicken SUCLG2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SUCLG2 involved in several pathways and played different roles in them. We selected most pathways SUCLG2 participated on our site, such as Citrate cycle (TCA cycle), Propanoate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUCLG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Citrate cycle (TCA cycle)SUCLG2;IDH3B;DLDH;PCXB;SDHB;SDHDB;MDH2;PCK1;PC
Propanoate metabolismACSS1;LDHAL6A;ACSS3;HADHA;HADHAA;DLDH;SUCLG2;PCCA;ACAT2
Metabolic pathwaysOXSR1;ACSM2;GUK1B;PCCA;CYP2U1;B3GNT3;DAD1;SDHA;PIGS
Carbon metabolismOGDHL;SUCLG1;PRPS2;GPT2L;PFKL;PDHA1;G6PD;SDSL;ALDOCB

SUCLG2 has several biochemical functions, for example, ATP binding, GTP binding, succinate-CoA ligase (GDP-forming) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SUCLG2 itself. We selected most functions SUCLG2 had, and list some proteins which have the same functions with SUCLG2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingUBE2E3;BMPR1AB;UBE2U;IP6K2;DDX21;CHTF18;TRIT1;NAV2;PRKCHA
GTP bindingGIMAP2;RAB1B;TUBB2B;DNM1A;GIMAP1;TUBG1;RAB39B;RAB4B;EEF1A1
succinate-CoA ligase (GDP-forming) activitySUCLG2;SUCLG1

SUCLG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUCLG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUCLG2.

USP19; DMWD; SGCG; AK1; MYC; CD247; SIRT4

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