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SUV39H2

Official Full Name

suppressor of variegation 3-9 homolog 2
Overview

Histone-lysine N-methyltransferase SUV39H2 is an enzyme that in humans is encoded by the SUV39H2 gene.
Synonyms

SUV39H2; suppressor of variegation 3-9 homolog 2 (Drosophila); histone-lysine N-methyltransferase SUV39H2; FLJ23414; KMT1B; H3-K9-HMTase 2; su(var)3-9 homolog 2; lysine N-methyltransferase 1B; histone H3-K9 methyltransferase 2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads
Assay Kits

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SUV39H2-209H	Recombinant Human SUV39H2 Protein, His-tagged	E.coli	His	48-410	Inquiry
Human	SUV39H2-29907TH	Recombinant Human SUV39H2	E.coli	N/A		Inquiry
Human	SUV39H2-3063H	Recombinant Human SUV39H2, GST-tagged	E.coli	GST	110-410aa	$319 / 25ug
Human	SUV39H2-472H	Recombinant Human SUV39H2, GST-tagged	E.coli	GST		Inquiry
Human	SUV39H2-1333HCL	Recombinant Human SUV39H2 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	SUV39H2-16262M	Recombinant Mouse SUV39H2 Protein	Mammalian Cell	His		Inquiry
Mouse	SUV39H2-8888M	Recombinant Mouse SUV39H2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	SUV39H2-8888M-B	Recombinant Mouse SUV39H2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	SUV39H2-3021C	Recombinant Chicken SUV39H2	Mammalian Cell	His		Inquiry
	Kit-1871	SUV39H2 Chemiluminescent Assay Kit		N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SUV39H2 Related Articles
SUV39H2 Related Research Area

SUV39H2 involved in several pathways and played different roles in them. We selected most pathways SUV39H2 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUV39H2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Lysine degradation	EHMT1;C2orf34;ALDH9A1;HYKK;ALDH3A2A;HADHAA;EHMT1B;HADHAB;COLGALT2

SUV39H2 has several biochemical functions, for example, histone methyltransferase activity (H3-K9 specific), protein binding, transcription regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUV39H2 itself. We selected most functions SUV39H2 had, and list some proteins which have the same functions with SUV39H2. You can find most of the proteins on our site.

Function	Related Protein
histone methyltransferase activity (H3-K9 specific)	SETDB2;SUV39H2;EHMT1;SUV39H1;EHMT2
protein binding	HSPA6;MMP20;AKAP6;SLC3A1;SF3A1;SH3GLB2;MYO15;MAP3K9;AIFM1
transcription regulatory region sequence-specific DNA binding	NFE2L2A;NONO;DDIT3;NKX3-1;GATA3;SFPQ;SOX4;MEF2AA;NR5A5
zinc ion binding	RXRAB;ESR2A;WTIP;ASTL;BMI1;CRIP1;NR2E1;RBCK1;RNF32

SUV39H2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUV39H2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUV39H2.

APPL2; PNMA1; HEL25; CEP70; RASSF1; PHF19; KCTD17; KLHDC4

Kudithipudi, S; Kusevic, D; et al. Non-radioactive Protein Lysine Methyltransferase Microplate Assay Based on Reading Domains. CHEMMEDCHEM 9:554-559(2014).

Rice, JC; Briggs, SD; et al. Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. MOLECULAR CELL 12:1591-1598(2003).

Histone Methyltransferase