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SUV420H1

  • Official Full Name

    suppressor of variegation 4-20 homolog 1

  • Overview

    This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants have been found for this gene.
  • Synonyms

    SUV420H1; suppressor of variegation 4-20 homolog 1 (Drosophila); histone-lysine N-methyltransferase SUV420H1; CGI 85; KMT5B; suv4-20h1; C630029K18Rik; su(var)4-20 homolog 1; lysine N-methyltransferase 5B; CGI85; CGI-85; MGC703; MGC21161; MGC118906; MGC118;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SUV420H1-210H Recombinant Human SUV420H1 Protein, GST-tagged Insect Cell GST 2-885
Human SUV420H1-31486TH Recombinant Human SUV420H1 E.coli N/A
Human SUV420H1-211H Recombinant Human SUV420H1 Protein, GST-tagged Insect Cell GST 2-393
Human SUV420H1-473H Recombinant Human SUV420H1, GST-tagged E.coli GST
Human SUV420H1-1332HCL Recombinant Human SUV420H1 293 Cell Lysate HEK293 N/A
Mouse SUV420H1-16263M Recombinant Mouse SUV420H1 Protein Mammalian Cell His
Mouse SUV420H1-8889M Recombinant Mouse SUV420H1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SUV420H1-8889M-B Recombinant Mouse SUV420H1 Protein Pre-coupled Magnetic Beads HEK293
Rat SUV420H1-5844R Recombinant Rat SUV420H1 Protein Mammalian Cell His
Rat SUV420H1-5503R-B Recombinant Rat SUV420H1 Protein Pre-coupled Magnetic Beads HEK293
Rat SUV420H1-5503R Recombinant Rat SUV420H1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SUV420H1-4571R Recombinant Rhesus monkey SUV420H1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SUV420H1-4387R Recombinant Rhesus Macaque SUV420H1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SUV420H1-4387R-B Recombinant Rhesus Macaque SUV420H1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SUV420H1-1726Z Recombinant Zebrafish SUV420H1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SUV420H1 Related Articles

SUV420H1 involved in several pathways and played different roles in them. We selected most pathways SUV420H1 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUV420H1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Lysine degradationSETD7;GLT25D2;GCDHB;DOT1L;SUV39H1;COLGALT2;AGPHD1;ALDH2;WHSC1

SUV420H1 has several biochemical functions, for example, histone methyltransferase activity (H4-K20 specific), histone-lysine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SUV420H1 itself. We selected most functions SUV420H1 had, and list some proteins which have the same functions with SUV420H1. You can find most of the proteins on our site.

Function Related Protein
histone methyltransferase activity (H4-K20 specific)SUV420H1;NSD1;SUV420H2;WHSC1
histone-lysine N-methyltransferase activityMLL1;WBP7;SUV420H1;MLL5;EZH2;WHSC1L1;SUV39H1B;SETD8A;SETDB1

SUV420H1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUV420H1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUV420H1.

YWHAQ; YWHAG; pagA; yezC; SMARCD1

Li, YL; Choi, PS; et al. MYC through miR-17-92 Suppresses Specific Target Genes to Maintain Survival, Autonomous Proliferation, and a Neoplastic State. CANCER CELL 26:262-272(2014).
Yokoyama, Y; Matsumoto, A; et al. Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity. BREAST CANCER RESEARCH 16:-(2014).
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