SUZ12
-
Official Full Name
SUZ12 polycomb repressive complex 2 subunit
-
Overview
This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009] -
Synonyms
SUZ12; SUZ12 polycomb repressive complex 2 subunit; CHET9; JJAZ1; polycomb protein SUZ12; chET 9 protein; joined to JAZF1 protein; suppressor of zeste 12 homolog; suppressor of zeste 12 protein homolog; chromatin precipitated E2F target 9 protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mammalian cells
- Wheat Germ
- Flag
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- His
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SUZ12-31487TH | Recombinant Human SUZ12 | Wheat Germ | N/A | 100 amino acids | |
Human | SUZ12-1330HCL | Recombinant Human SUZ12 293 Cell Lysate | HEK293 | N/A | ||
Human | SUZ12-35H | Recombinant Human SUZ12 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Human | SUZ12-763HFL | Recombinant Full Length Human SUZ12 Protein, C-Flag-tagged | Mammalian cells | Flag | ||
Human | SUZ12-2744H | Recombinant Human SUZ12 Protein, His-tagged | E.coli | N-His | Leu448-Phe639 | |
Human | SUZ12-2141H-B | Recombinant Human SUZ12 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | SUZ12-2141H | Recombinant Human SUZ12 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | Suz12-6234M | Recombinant Mouse Suz12 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
- Involved Pathway
- Protein Function
- Interacting Protein
- SUZ12 Related Articles
- SUZ12 Related Research Area
SUZ12 involved in several pathways and played different roles in them. We selected most pathways SUZ12 participated on our site, such as Cellular Senescence, Cellular responses to stress, Chromatin modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUZ12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Cellular Senescence | IGFBP7;PHC2;HIST1H1A;BMI1A;LMNB1;PHC3;MINK1;RING1;TNIK |
Cellular responses to stress | BAG3;ATG101;HIST3H2BB;ASF1A;CDKN2D;UVRAG;KIAA1967;CEBPB;H3F3D |
Chromatin modifying enzymes | BRPF3;SETD3;ACTL6A;MSL1A;PBRM1;MSL2;ARID4A;PADI2;PHF2 |
Chromatin organization | MSL1;MBD3B;SMYD2A;ELP4;SUZ12;BRPF1;JMJD6;KDM5D;JHDM1D |
Epigenetic regulation of gene expression | JARID2;DNMT3A;TET1;SAP30L;DNMT1;H3F3B.1;TAF1D;UHRF1;DNMT3L |
Gene Expression | ZNF582;PEAK1;ZBTB8OS;PPARAA;AIMP2;ZNF566;COX18;ZNF713;DDX6 |
Oxidative Stress Induced Senescence | SUZ12;SCMH1;BMI1A;PHC2;SUZ12A;PHC3;RNF2;CBX4;TNIK |
PKMTs methylate histone lysines | SUZ12A;AEBP2;SETD3;PRDM16;SMYD2;SUZ12B;EHMT2;SMYD2A;ATF7IP |
SUZ12 has several biochemical functions, for example, RNA binding, RNA polymerase II core promoter sequence-specific DNA binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUZ12 itself. We selected most functions SUZ12 had, and list some proteins which have the same functions with SUZ12. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
RNA binding | ILF3B;PATL1;EMG1;MRPL3;PAPOLB;CNBPA;MKI67IP;RPL19;ELAVL4 |
RNA polymerase II core promoter sequence-specific DNA binding | NSD1;SMAD5;HOXB3;YAP1;PAX6;GATA3;RREB1;EP300;SMYD3 |
chromatin binding | TICRR;HDGFRP2;SIN3B;ASF1A;TOP2B;REST;CDCA5;RUNX2;NR5A2 |
histone methyltransferase activity | PRDM13;CARM1;SUV39H1;EZH2;PRMT6;EED;SUZ12;PRMT1;PRMT2 |
metal ion binding | CD209A;PCGF5A;PTGS1;MLL5;AKAP8L;RXRBA;CYP4T8;CYP2X7;ROCK2A |
methylated histone binding | JHDM1D;ING2;UHRF1;RAG2;MSL3;PHF2;CBX7;RRP8;ING5 |
protein binding | MPPE1;WBP11;CCL3;DUSP21;RAB11FIP5;CDK8;COX4I1;PDZD3;CNOT4 |
SUZ12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUZ12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUZ12.
EZH2; CUL4B
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All SUZ12 Products
Required fields are marked with *
My Review for All SUZ12 Products
Required fields are marked with *