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SV2A

Official Full Name

synaptic vesicle glycoprotein 2A
Overview

Synaptic vesicle glycoprotein 2A is a ubiquitous synaptic vesicle protein that in humans is encoded by the SV2A gene.The protein is targeted by the anti-epileptic drug (AED) levetiracetam.
Synonyms

SV2A; synaptic vesicle glycoprotein 2A; KIAA0736; SV2; OTTHUMP00000014065; Synaptic vesicle glycoprotein 2; Synaptic vesicle protein 2a; OTTHUMP00000014066;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Bovine
Cynomolgus Monkey
Human
Mouse
Rat

Source

HEK293
Mammalian Cell
Yeast

Tag

His
His (Fc)
Avi
Myc
His|Myc
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SV2A-1329HCL	Recombinant Human SV2A 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	SV2A-16266M	Recombinant Mouse SV2A Protein	Mammalian Cell	His		Inquiry
Mouse	SV2A-8891M-B	Recombinant Mouse SV2A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	SV2A-8891M	Recombinant Mouse SV2A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SV2A-5846R	Recombinant Rat SV2A Protein	Mammalian Cell	His		Inquiry
Rat	SV2A-5505R	Recombinant Rat SV2A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SV2A-5505R-B	Recombinant Rat SV2A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Bovine	SV2A-5068B	Recombinant Bovine SV2A protein, His&Myc-tagged	HEK293	His&Myc	1-169aa	Inquiry
Bovine	SV2A-2274B	Recombinant Bovine SV2A Protein (1-169 aa), His-Myc-tagged	Yeast	His/Myc	1-169 aa	Inquiry
Cynomolgus Monkey	SV2A-993C	Recombinant Cynomolgus SV2A Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	SV2A-736C-B	Recombinant Cynomolgus Monkey SV2A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Cynomolgus Monkey	SV2A-736C	Recombinant Cynomolgus Monkey SV2A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SV2A Related Articles

SV2A involved in several pathways and played different roles in them. We selected most pathways SV2A participated on our site, such as ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SV2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
ECM-receptor interaction	Npnt;IBSP;GP1BB;COL4A1;TNN;LAMC2;COL2A1A;VTNB;ITGB5

SV2A has several biochemical functions, for example, protein kinase binding, receptor activity, transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SV2A itself. We selected most functions SV2A had, and list some proteins which have the same functions with SV2A. You can find most of the proteins on our site.

Function	Related Protein
protein kinase binding	CDC42;SCN5A;SPRED2;DNAJA3;HSP90AB1;TP73;MAP3K2;ILK;FAM83B
receptor activity	LILRA2;NOTCH4;LRRN2;GUCY1A3;ADCYAP1R1;MED13;NOTCH1;GRIN1B;NLGN1
transmembrane transporter activity	SLC2A15B;ATP5B;CX43;SLC2A9L1;SLC2A15A;SLC22A13;ATP5O;ATP5F1;AQP1

SV2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SV2A here. Most of them are supplied by our site. Hope this information will be useful for your research of SV2A.

ETS1; ATXN1; P

Strotmeier, J; Mahrhold, S; et al. Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A. FEBS LETTERS 588:1087-1093(2014).

Sgro, AE; Bajjalieh, SM; et al. Single-Axonal Organelle Analysis Method Reveals New Protein-Motor Associations. ACS CHEMICAL NEUROSCIENCE 4:277-284(2013).