SYMPK
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Official Full Name
Symplekin
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Overview
This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. -
Synonyms
SPK; SYM; FLJ27092; SYMPK; symplekin; OTTHUMP00000196465;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- GST
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SYMPK-3070H | Recombinant Human SYMPK, GST-tagged | E.coli | GST | N-term-361aa | |
| Human | SYMPK-8135H | Recombinant Human SYMPK protein, His & T7-tagged | E.coli | His/T7 | Met1~Lys347 (Accession # Q92797) |
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| Human | SYMPK-1729HCL | Recombinant Human SYMPK cell lysate | N/A |
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| Human | SYMPK-4570H | Recombinant Human SYMPK Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | SYMPK-3050H | Recombinant Human SYMPK Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Mouse | Sympk-1670M | Recombinant Mouse Sympk protein, His & T7-tagged | E.coli | His/T7 | Met1~Asp75 (Accession # Q80X82) |
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| Mouse | Sympk-6246M | Recombinant Mouse Sympk Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
SYMPK involved in several pathways and played different roles in them. We selected most pathways SYMPK participated on our site, such as mRNA surveillance pathway, Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYMPK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA surveillance pathway | ETF1;PPP1CAB;PABPC1B;PABPC1;PPP2R3A;SMG5;PCF11;NXF2;PPP2R5C |
| Tight junction | CLDN1;PARD6GB;CLDN11A;PRKCE;MYL10;MYH11A;CLDND;MYH11;PARD6A |
SYMPK has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYMPK itself. We selected most functions SYMPK had, and list some proteins which have the same functions with SYMPK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | COPS7A;RAD1;OSTC;FUNDC1;CENPT;RB1;MAP3K11;AMPD2;GPANK1 |
SYMPK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYMPK here. Most of them are supplied by our site. Hope this information will be useful for your research of SYMPK.
CPSF2; CPSF3; MCC; MAGEA6; WWOX; GSTK1; RIN3; ssdna_dt; VPS26A; CPSF4; FN1; P4HB; MAPK3; CSTF2; Id2
- Q&As
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