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SYNJ1

  • Official Full Name

    synaptojanin 1

  • Overview

    has inositol 5-phosphatase activity; interacts with dynamin to play a role in synaptic vesicle recycling [RGD, Feb 2006]
  • Synonyms

    SYNJ1; synaptojanin 1; synaptojanin-1; synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SYNJ1-3073H Recombinant Human SYNJ1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SYNJ1-3074H Active Recombinant Human SYNJ1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Synj1-247M Recombinant Mouse Synj1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat SYNJ1-5868R Recombinant Rat SYNJ1 Protein Mammalian Cell His
Rat SYNJ1-5527R Recombinant Rat SYNJ1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SYNJ1-5527R-B Recombinant Rat SYNJ1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SYNJ1-1617Z Recombinant Zebrafish SYNJ1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SYNJ1 involved in several pathways and played different roles in them. We selected most pathways SYNJ1 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYNJ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inositol phosphate metabolismPIK3C3;PLCB3;MTMR4;NUDT10;PIP5K1C;PLCZ1;PI4KB;PLCD1A;NUDT4B
Metabolic pathwaysAK9;ATP5IA;DUT;CYP2B6;ADA;UOX;CYP2C8;OGDH;NDUFB3
Phosphatidylinositol signaling systemPTEN;IP6K2;CALML5;PIK3R1;PLCB2;CALM;INPP5J;INPP1;PIK3R3B

SYNJ1 has several biochemical functions, for example, hydrolase activity, nucleic acid binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYNJ1 itself. We selected most functions SYNJ1 had, and list some proteins which have the same functions with SYNJ1. You can find most of the proteins on our site.

Function Related Protein
hydrolase activityTMPRSS13A;SMG6;NUDT19;ABHD16A;Ctsl;PA2G4B;IIGP1;LACTB;Chil3
nucleic acid bindingTIGD5;ANG3;MARF1;ZIC2A;SSX3;SP9;REV3L;GATAD2AB;ZNF728
nucleotide bindingRMI1;MYEF2;RAB12;TIA1;MKNK2B;MYHZ1.1;GNA11B;ABCC12;ERBB4A
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activitySYNJ1;INPP5K
phosphoric ester hydrolase activitySMG6;RNASEKB;TMPPE;GDPD4;MEIOB;REXO1;EXO5;FBP1A;SYNJ1

SYNJ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYNJ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYNJ1.

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Is SYNJ1 expression limited to the nervous system? 11/04/2020

SYNJ1 is primarily expressed in the nervous system, emphasizing its role in neuronal function and synaptic transmission.

How does SYNJ1 dysfunction contribute to synaptic dysfunction in neurodegenerative diseases? 10/07/2020

SYNJ1 dysfunction may lead to impaired synaptic vesicle recycling, disrupting normal neurotransmission and contributing to synaptic dysfunction observed in neurodegenerative diseases.

How is SYNJ1 protein implicated in neurodegenerative diseases? 11/25/2017

Can alterations in SYNJ1 expression be detected in cerebrospinal fluid or blood samples? 11/01/2016

Research is underway to explore the feasibility of detecting SYNJ1 alterations in cerebrospinal fluid or blood as potential diagnostic or prognostic markers for neurodegenerative diseases.

How do SYNJ1 mutations contribute to Parkinson's disease pathogenesis? 01/17/2016

SYNJ1 mutations are thought to disrupt synaptic vesicle endocytosis, leading to impaired neurotransmitter release and contributing to the pathogenesis of Parkinson's disease.

Customer Reviews (3)

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Reviews
07/27/2020

    This protein, manufactured with utmost precision, provides reliable and consistent results, ensuring the accuracy and reproducibility of your research findings.

    12/23/2019

      Its purity and functional integrity guarantee optimal performance in a wide range of experimental applications.

      09/30/2019

        Their team of experts is readily available to assist you with any inquiries or challenges you may encounter during your experiments.

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