T
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Official Full Name
T, brachyury homolog (mouse)
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Overview
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] -
Synonyms
T; T, brachyury homolog (mouse); TFT; SAVA; brachyury protein; protein T; T brachyury homolog;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Protein Pre-coupled Magnetic Beads
- Chicken
- Enterobacteria phage T4 (Bacteriophage T4)
- Human
- Mouse
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mouse
- Rat
- Wheat Germ
- hIgG
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | T-27672TH | Recombinant Human T | Wheat Germ | N/A | 99 amino acids | |
Human | T-27668TH | Recombinant Human T | Wheat Germ | N/A | 377 amino acids | |
Human | T-1294HCL | Recombinant Human T 293 Cell Lysate | HEK293 | N/A | ||
Human | TNFRSF25-10H | Active Recombinant Human TNFRSF25 Protein, hIgG/His-tagged | Insect Cell | hIgG/His | 417 | |
Human | DMAB32033 | Mouse Anti-TRIM27 Monoclonal Antibody | Mouse | N/A | ||
Human | T-130H | Recombinant Human T Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | T-510HF | Recombinant Full Length Human T Protein | In Vitro Cell Free System | 377 amino acids | ||
Mouse | T-16350M | Recombinant Mouse T Protein | Mammalian Cell | His | ||
Mouse | DMAB36387 | Rat Anti-Timd2 Monoclonal Antibody | Rat | N/A | ||
Mouse | T-8938M | Recombinant Mouse T Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | T-8938M-B | Recombinant Mouse T Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | T-6267M | Recombinant Mouse T Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | DMAB36386 | Rat Anti-Timd2 Monoclonal Antibody | Rat | N/A | ||
Enterobacteria phage T4 (Bacteriophage T4) | RFL22746EF | Recombinant Full Length Enterobacteria Phage T4 Lysis Protein(T) Protein, His-Tagged | E.coli expression system | His | Full Length (1-218) | |
Chicken | T-6500C | Recombinant Chicken T | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- T Related Articles
- T Related Gene Family
T involved in several pathways and played different roles in them. We selected most pathways T participated on our site, such as Cardiac Progenitor Differentiation, Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with T were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cardiac Progenitor Differentiation | BMP1;TBX20;LIN28B;SIRPA;NIPAL1;T;ROR2;ZFP42;IRX4 |
Regulation of Wnt-mediated beta catenin signaling and target gene transcription | MYOG;CDX4;IGF2BP1;KRT1;TLE2;SALL4;TNIK;TLE4;TCF4 |
T has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by T itself. We selected most functions T had, and list some proteins which have the same functions with T. You can find most of the proteins on our site.
Function | Related Protein |
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RNA polymerase II activating transcription factor binding | ISL1;ZFPM1;T;SIN3A;NEUROD1;SETD3;CTNNB1;TP53BP1;EGR2 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | FLI1;HNRNPK;MYB;PDX1;RAX;NKX6-2;PLAG1;CEBPB;ZIC1 |
RNA polymerase II distal enhancer sequence-specific DNA binding | NR5A1;PROP1;NFKB1;PAX4;BACH1A;NFE2L1;BACH2;POU4F1;SPI1 |
RNA polymerase II transcription factor binding | SPI1;TBX6;PITX2;HCLS1;ID4;GATA1A;TOX2;T;GSK3B |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | HNF1B;NFIX;GLI1;MEF2A;HNF4A;SNAI2;IRF8;LEF1;NKX2 |
transcription factor activity, sequence-specific DNA binding | CREBL2;HOMEZA;DRAP1;HOXA3A;MECP2;MAFGA;SUPT6H;NCOR1;AATF |
transcriptional repressor activity, RNA polymerase II transcription factor binding | CREBBP;MINA;AHRR;BHLHE40;MLIP;TBX6;ELP2;T;EOMES |
T has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with T here. Most of them are supplied by our site. Hope this information will be useful for your research of T.
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