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T

  • Official Full Name

    T, brachyury homolog (mouse)

  • Overview

    The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
  • Synonyms

    T; T, brachyury homolog (mouse); TFT; SAVA; brachyury protein; protein T; T brachyury homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Enterobacteria phage T4 (Bacteriophage T4)
  • Human
  • Mouse
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mouse
  • Rat
  • Wheat Germ
  • hIgG
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human T-27672TH Recombinant Human T Wheat Germ N/A 99 amino acids
Human T-27668TH Recombinant Human T Wheat Germ N/A 377 amino acids
Human T-1294HCL Recombinant Human T 293 Cell Lysate HEK293 N/A
Human TNFRSF25-10H Active Recombinant Human TNFRSF25 Protein, hIgG/His-tagged Insect Cell hIgG/His 417
Human DMAB32033 Mouse Anti-TRIM27 Monoclonal Antibody Mouse N/A
Human T-130H Recombinant Human T Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human T-510HF Recombinant Full Length Human T Protein In Vitro Cell Free System 377 amino acids
Mouse T-16350M Recombinant Mouse T Protein Mammalian Cell His
Mouse DMAB36387 Rat Anti-Timd2 Monoclonal Antibody Rat N/A
Mouse T-8938M Recombinant Mouse T Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse T-8938M-B Recombinant Mouse T Protein Pre-coupled Magnetic Beads HEK293
Mouse T-6267M Recombinant Mouse T Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DMAB36386 Rat Anti-Timd2 Monoclonal Antibody Rat N/A
Enterobacteria phage T4 (Bacteriophage T4) RFL22746EF Recombinant Full Length Enterobacteria Phage T4 Lysis Protein(T) Protein, His-Tagged E.coli expression system His Full Length (1-218)
Chicken T-6500C Recombinant Chicken T Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • T Related Articles
  • T Related Gene Family

T involved in several pathways and played different roles in them. We selected most pathways T participated on our site, such as Cardiac Progenitor Differentiation, Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with T were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cardiac Progenitor DifferentiationBMP1;TBX20;LIN28B;SIRPA;NIPAL1;T;ROR2;ZFP42;IRX4
Regulation of Wnt-mediated beta catenin signaling and target gene transcriptionMYOG;CDX4;IGF2BP1;KRT1;TLE2;SALL4;TNIK;TLE4;TCF4

T has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by T itself. We selected most functions T had, and list some proteins which have the same functions with T. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II activating transcription factor bindingISL1;ZFPM1;T;SIN3A;NEUROD1;SETD3;CTNNB1;TP53BP1;EGR2
RNA polymerase II core promoter proximal region sequence-specific DNA bindingFLI1;HNRNPK;MYB;PDX1;RAX;NKX6-2;PLAG1;CEBPB;ZIC1
RNA polymerase II distal enhancer sequence-specific DNA bindingNR5A1;PROP1;NFKB1;PAX4;BACH1A;NFE2L1;BACH2;POU4F1;SPI1
RNA polymerase II transcription factor bindingSPI1;TBX6;PITX2;HCLS1;ID4;GATA1A;TOX2;T;GSK3B
transcription factor activity, RNA polymerase II distal enhancer sequence-specific bindingHNF1B;NFIX;GLI1;MEF2A;HNF4A;SNAI2;IRF8;LEF1;NKX2
transcription factor activity, sequence-specific DNA bindingCREBL2;HOMEZA;DRAP1;HOXA3A;MECP2;MAFGA;SUPT6H;NCOR1;AATF
transcriptional repressor activity, RNA polymerase II transcription factor bindingCREBBP;MINA;AHRR;BHLHE40;MLIP;TBX6;ELP2;T;EOMES

T has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with T here. Most of them are supplied by our site. Hope this information will be useful for your research of T.

Yang, YR; Feng, JD; et al. Immune Responses to a Recombinant Rv0057-Rv1352 Fusion Protein of Mycobacterium tuberculosis. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:39-48(2015).
Law, JKY; Susloparova, A; et al. Human T cells monitored by impedance spectrometry using field-effect transistor arrays: A novel tool for single-cell adhesion and migration studies. BIOSENSORS & BIOELECTRONICS 67:170-176(2015).
IL
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