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TAE1

  • Official Full Name

    TAE1 Tae1p [ Saccharomyces cerevisiae S288c ]

  • Overview

    Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of the ribosomal proteins RPL12A, RPL12B, RPS25A and RPS25B.
  • Synonyms

    TAE1; Tae1p; YBR261C, NTM1;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TAE1-7904H Recombinant Human TAE1 E.coli N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TAE1 involved in several pathways and played different roles in them. We selected most pathways TAE1 participated on our site, such as Choline metabolism in cancer, Effects of PIP2 hydrolysis, G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Choline metabolism in cancerWASF1;PLA2G4A;PDGFD;DGKZ;PIP5K1C;SP1;RALGDS;MAPK3;PDPK1
Effects of PIP2 hydrolysisDGKA;ABHD12;TAE1;ABHD6B;TRPC3;DGKG;MGLL;TRPC7;RASGRP2
G alpha (q) signalling eventsANXA1A;NMBA;QRFP;EDNRAB;CHRM5;TAC3;CHRM3;FPR-RS3;UTS2D
GPCR downstream signalingDRD5;GPR68;CCR1;PTHLH;OXGR1;CALCRL;PROK2;CASR;NMBB
Gastrin-CREB signalling pathway via PKC and MAPKTAC1;NMBA;EDN2;DGKQ;ANXA1A;RASGRP2;NPFFR2;CASR;PMCH
Glycerolipid metabolismAGPAT9;MOGAT1;PPAP2C;DGKZ;TAE1;LIPC;ALDH2.1;DGAT1;ALDH9A1
Glycerophospholipid metabolismPCYT1AA;MBOAT1;CDS1;LYPLA2;PLA2G4C;DGKZ;LPIN2;CDS2;GPAM
HemostasisGATA6;S100A10B;SLC3A2A;SLC3A2B;CABLES2;STXBP3A;TAE1;TREM1;GATA1A

TAE1 has several biochemical functions, for example, ATP binding, diacylglycerol kinase activity, enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAE1 itself. We selected most functions TAE1 had, and list some proteins which have the same functions with TAE1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCAMK1GB;DDX3;PLK2;PPIP5K1;DDX27;RFC4;DDX39;SLKA;FYNB
diacylglycerol kinase activityDGKQ;DGKA;TAE1;AGK;DGKZ;DGKE;DGKB;DGKAA;DGKD
enzyme inhibitor activityCALU;UGT1A7;ATPIF1A;UGT1A9;OAZ1A;PDE6G;SLN;PDE6H;CD46
lipid kinase activityTAE1;PIK3C2B;DGKZ
metal ion bindingCMC1;KLK1B4;IDO1;PLA2G4D;DMRTC2;ZSCAN4;ZNF384L;NME2;ZNF16
protein C-terminus bindingVGLL2;TBL1X;PIAS4;MSH2;DBNL;NEFL;SHANK2;KSR1;MRE11A
protein bindingMTCH1;CD247;CIZ1;KIRREL3;BAD;NELL2;ABCE1;EIF2B4;RASL10B

TAE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAE1.

ILV1; CTT1; PIS1; SNA3; CTA1; HSP26; SEC18; ycp7_yeast; RNQ1; CAT2; MAC1; nnrd_yeast; PCH2; PBP2; yhr2_yeast; phs_yeast; QNS1; UBA4; APE4; MBB1

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