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TBL2

Official Full Name

transducin (beta)-like 2
Overview

This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
Synonyms

TBL2; transducin (beta)-like 2; transducin beta-like protein 2; DKFZP43N024; WBSCR13; Williams Beuren syndrome chromosome region 13; WS betaTRP; DKFZp434N024; MGC134739; TBL 2; Transducin (beta) like 2; Transducin beta like 2; Transducin beta like 2 protein; WBSCR 13; Williams Beuren syndrome chromosomal region 13 protein; WS beta transducin repeats protein; WS beta-transducin repeats protein; Williams-Beuren syndrome chromosome region 13; WS-betaTRP;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TBL2-1212HCL	Recombinant Human TBL2 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	TBL2-16515M	Recombinant Mouse TBL2 Protein	Mammalian Cell	His	Inquiry
Mouse	TBL2-9049M	Recombinant Mouse TBL2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	TBL2-9049M-B	Recombinant Mouse TBL2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	TBL2-12036Z	Recombinant Zebrafish TBL2	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TBL2 Related Articles

TBL2 involved in several pathways and played different roles in them. We selected most pathways TBL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TBL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TBL2 has several biochemical functions, for example, phosphoprotein binding, poly(A) RNA binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBL2 itself. We selected most functions TBL2 had, and list some proteins which have the same functions with TBL2. You can find most of the proteins on our site.

Function	Related Protein
phosphoprotein binding	DPYSL3;PRKCSH;TRPV1;PITX2;CBX4;GPRIN1;LRP11;URI1;TBK1
poly(A) RNA binding	HIST1H4K;PTCD1;LUC7L3;DARS;ACAA2;SUMO1;SARS2;FARSA;BRIX1
protein kinase binding	DAXX;PAK2;PTPRC;PIH1D1;CD3E;SMAD3;STK11IP;RB1CC1;TSACC
translation initiation factor binding	TRIM32;EIF2B4;EIF3C;LARP1;POLR2D;LIN28A;ZFP259;EIF3F;EIF3M

TBL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBL2.

PDPK1; USP44; ssdna_dtdg; MYC; ESR1; AGO1

Li, JW; Wang, J; et al. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO JOURNAL 19:4342-4350(2000).

Nawy, S; et al. The metabotropic receptor mGluR6 may signal through G(o), but not phosphodiesterase, in retinal bipolar cells. JOURNAL OF NEUROSCIENCE 19:2938-2944(1999).