Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

TDP2

  • Official Full Name

    tyrosyl-DNA phosphodiesterase 2

  • Overview

    This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
  • Synonyms

    EAP2; AD022; TTRAP; MGC9099; dJ30M3.3; MGC111021; RP1-30M3.3; tyrosyl-DNA phosphodiesterase 2; EAPII; OTTHUMP00000016091; OTTHUMP00000016092; ETS1-associated protein 2; ETS1-associated protein II; tyr-DNA phosphodiesterase 2; 5"-Tyr-DNA phosphodiesterase; 5"-tyrosyl-DNA phosphodiesterase; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; TDP2; tyrosyl-DNA phosphodiesterase 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TDP2-7580H Recombinant Human TDP2, His-tagged E.coli His 1-362aa
Human TDP2-664HCL Recombinant Human TTRAP 293 Cell Lysate HEK293 N/A
Human TDP2-6706H Recombinant Human TDP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse TDP2-16603M Recombinant Mouse TDP2 Protein Mammalian Cell His
Mouse TDP2-9104M Recombinant Mouse TDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tdp2-6348M Recombinant Mouse Tdp2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TDP2-9104M-B Recombinant Mouse TDP2 Protein Pre-coupled Magnetic Beads HEK293
Rat TDP2-5999R Recombinant Rat TDP2 Protein Mammalian Cell His
Rat TDP2-5658R Recombinant Rat TDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TDP2-5658R-B Recombinant Rat TDP2 Protein Pre-coupled Magnetic Beads HEK293
Chicken TDP2-4713C Recombinant Chicken TDP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TDP2 involved in several pathways and played different roles in them. We selected most pathways TDP2 participated on our site, such as CD40/CD40L signaling, DNA Double-Strand Break Repair, DNA Repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with TDP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
CD40/CD40L signalingMYC;JAK3;TDP2
DNA Double-Strand Break RepairEME2;RAD9B;TIPIN;BARD1;BAZ1B;FUZ;EYA4;CHEK1;KDM4A
DNA RepairCOPS2;PIAS3;PPP4CA;KIAA1530;USP10;INO80E;CETN2;KIAA0101;DCLRE1A
Nonhomologous End-Joining (NHEJ)TDP2B;PAXIP1;TDP2;TDP1;RIF1

TDP2 has several biochemical functions, for example, 5-tyrosyl-DNA phosphodiesterase activity, magnesium ion binding, manganese ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TDP2 itself. We selected most functions TDP2 had, and list some proteins which have the same functions with TDP2. You can find most of the proteins on our site.

Function Related Protein
5-tyrosyl-DNA phosphodiesterase activityTDP2;TDP2B
magnesium ion bindingNT5C1A;CIB4;DYRK2;CIB2;DCTPP1;ENO1A;PI4K2A;NT5C3A;TESC
manganese ion bindingSOD2;PPM1N;PEPD;FAM20C;GALNT1;MTPAP;TDP2B;B4GALT7;B4GALT1
nuclease activityDNA2;RNASEKA;REXO4;EAR1;RNASEL2;EAR3;DROSHA;EAR4;FANCM
protein bindingNCAM1A;PPP1R37;PRX;IL1R2;IKBKE;NRBP1;ENTPD1;LANCL1;WDR83
single-stranded DNA bindingLRPPRC;DMC1;SSBP1;LONP1;CNBP;TSNAX;IGHMBP2;TDP1;TTC6
transcription corepressor activityPROX1;RBFOX2;HDAC9;ZHX1;ZNF593;SIAH2;ZFPM1;FEV;HDAC7A
tyrosyl-RNA phosphodiesterase activity

TDP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TDP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TDP2.

SRPK2; DLX3; SKIL; ETS1; PSEN1; ATXN1; JAM2; RAB11A; SMAD3; TAP1; ATP5G2; EPS8; MAPK6; q81xc2_bacan; AKAP9; C2orf88; SNX13

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All TDP2 Products

Required fields are marked with *

My Review for All TDP2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends