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TFB2M

  • Official Full Name

    transcription factor B2, mitochondrial

  • Overview

    Dimethyladenosine transferase 2, mitochondrial is an enzyme that in humans is encoded by the TFB2M gene.
  • Synonyms

    TFB2M; transcription factor B2, mitochondrial; dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; Hkp1; HCV NS5A transactivated protein 5; Mitochondrial 12S rRNA dimethylase 2; mitochondrial; Mitochondrial transcription factor B2; mtTFB2; N-adenosyl(rRNA) dimethyltransferase 2; S adenosylmethionine 6 N, N adenosyl(rRNA) dimethyltransferase 2; Dimethyladenosine transferase 2; h-mtTFB; h-mtTFB2; HCV NS5A-transactivated protein 5; Hepatitis C virus NS5A-transactivated protein 5; hTFB2M; Mitochondrial dimethyladenosine transferase 2; mtTFB; NS5ATP5; S-adenosylmethionine-6-N; TFB2M_HUMAN; Transcription Factor B2; OTTHUMP00000037974; S-adenos;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TFB2M-7205H Recombinant Human Transcription Factor B2, Mitochondrial, His-tagged E.coli His 20-396aa
Human TFB2M-3195H Recombinant Human TFB2M, His-tagged E.coli His c-221aa
Human TFB2M-1580H Recombinant Human TFB2M protein E.coli N/A
Human TFB2M-1135HCL Recombinant Human TFB2M 293 Cell Lysate HEK293 N/A
Human TFB2M-696H Recombinant Human TFB2M Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Tfb2m-1131M Recombinant Mouse Tfb2m Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat TFB2M-6026R Recombinant Rat TFB2M Protein Mammalian Cell His
Rat TFB2M-5685R-B Recombinant Rat TFB2M Protein Pre-coupled Magnetic Beads HEK293
Rat TFB2M-5685R Recombinant Rat TFB2M Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TFB2M-6345Z Recombinant Zebrafish TFB2M Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TFB2M Related Articles

TFB2M involved in several pathways and played different roles in them. We selected most pathways TFB2M participated on our site, such as Energy Metabolism, Gene Expression, Mitochondrial Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFB2M were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Energy MetabolismMEF2B;TFB2M;UCP3;GABPA;MYBBP1A;TFB1M;UCP2;ESRRA;PPARGC1B
Gene ExpressionSNAPC4;POP1;TFB2M;EEF1A1;ZNF10;CCNT2B;SNRNP48;EEF1G;NR5A1A
Mitochondrial Gene ExpressionMTERFD1;ESRRA;POLRMT;PPARGC1B;TFB2M;PPRC1;TFB1M
Mitochondrial biogenesisGABPA;ESRRA;PPARGC1B;MTERF;PPRC1;POLG2;GABPB1;C10orf2;POLRMT
Mitochondrial transcription initiationPOLRMT;TFB2M
Organelle biogenesis and maintenanceTCTEX1D2;TTBK2;RPGRIP1L;POLG2;CCDC123;IFT52;HSPB11;BBS4;POLRMT
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionGTF3C4;GTF3AB;POU2F1B;SNAPC1A;ZFP143;SNAPC4;GTF3A;SNAPC1B;NFIC
Transcription from mitochondrial promotersTFB2M;POLRMT;MTERF

TFB2M has several biochemical functions, for example, poly(A) RNA binding, rRNA (adenine-N6,N6-)-dimethyltransferase activity, transcription cofactor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TFB2M itself. We selected most functions TFB2M had, and list some proteins which have the same functions with TFB2M. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingHSPE1;EDF1;SRRT;TPT1;WDR6;SSBP1;TRIM28;FAM98A;HSP90AB1
rRNA (adenine-N6,N6-)-dimethyltransferase activityPRMT8B;FAM86;TRMT10B;TRMT10C;PRDM11;TFB2M;METTL21D;RNMTL1B;RNMTL1A
transcription cofactor activityLDB1B;TFDP2;POU2AF1;PHF21A;MED17;PIR;LPXN;PSMC5;NFE2L1

TFB2M has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFB2M here. Most of them are supplied by our site. Hope this information will be useful for your research of TFB2M.

TFAM; PHLDA3; ssrna_ug; C1qbp; Nek2; TUBG1; RAB4B; Ppp2ca; Gpkow; Cep131; Nup188; Tnpo1; Samm50; GAR1

Bao, L; Cai, XX; et al. Grape seed procyanidin B2 ameliorates mitochondrial dysfunction and inhibits apoptosis via the AMP-activated protein kinase-silent mating type information regulation 2 homologue 1-PPAR gamma co-activator-1 alpha axis in rat mesangial cells under high-dose glucosamine. BRITISH JOURNAL OF NUTRITION 113:35-44(2015).
Hayashi, G; Shen, Y; et al. Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia. HUMAN MOLECULAR GENETICS 23:6838-6847(2014).
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