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TFDP2

Official Full Name

transcription factor Dp-2 (E2F dimerization partner 2)
Overview

The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants.
Synonyms

TFDP2; transcription factor Dp-2 (E2F dimerization partner 2); transcription factor Dp-2; Dp 2; DP2; FLJ39131; DKFZp313O196;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TFDP2-3199H	Recombinant Human TFDP2, GST-tagged	E.coli	GST	N-term-350aa	$319 / 25ug
Human	TFDP2-013H	Recombinant Human TFDP2 Protein, His-tagged	E.coli	His		Inquiry
Human	TFDP2-1131HCL	Recombinant Human TFDP2 293 Cell Lysate	HEK293	N/A		Inquiry
Rhesus Macaque	TFDP2-4678R	Recombinant Rhesus monkey TFDP2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	TFDP2-4494R	Recombinant Rhesus Macaque TFDP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	TFDP2-4494R-B	Recombinant Rhesus Macaque TFDP2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	TFDP2-9803Z	Recombinant Zebrafish TFDP2	Mammalian Cell	His		Inquiry
Chicken	TFDP2-4096C	Recombinant Chicken TFDP2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
TFDP2 Related Articles

TFDP2 involved in several pathways and played different roles in them. We selected most pathways TFDP2 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFDP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell cycle	CDC14A;SMAD3;CENPP;HDAC2;GOLGA2;NUF2;PHF8;YWHAB;RBBP4

TFDP2 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFDP2 itself. We selected most functions TFDP2 had, and list some proteins which have the same functions with TFDP2. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	MYCN;SNAPC3;ARID5A;HIST1H2AL;HIST1H2BA;ISL2;ZNF2;KIF4A;HER8A
RNA polymerase II transcription factor activity, sequence-specific DNA binding	ELF2B;ZNF202;ZMYM5;SIM1;ELF5;FOXJ1A;OVOL2;FOXD1L;ZNF444
protein binding	NMRK1;FIGNL1;TEAD2;STK25;ARHGDIA;EIF4E;CUL2;ATF3;MRPL20
protein domain specific binding	RQCD1;WNT3;CALM1;ACTN2;GSN;FOXA1;CEP68;SLC34A2;RAB6A
transcription cofactor activity	ZFP667;PTPN14;ZNF671;ZFP865;HES6;ANKRA2;IRF3;KAT2B;ZMYND11
transcription factor activity, sequence-specific DNA binding	IRF3;ZSCAN16;FBXW7;DMRTA2;LBX1;ZKSCAN17;POU2F1A;NEUROD1;KDM3A
transcription factor binding	UBE2I;EPN1;TFDP1;JUNB;ENPP2;HDAC11;HDAC2;PRKDC;MYOD1

TFDP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFDP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TFDP2.

E2F6; E2F4; RBL2; E7; RB1; YWHAE; LIN9; LIN54; LIN37

Chen, C; Lodish, HF; et al. Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis. EXPERIMENTAL HEMATOLOGY 42:464-476(2014).

Wang, B; Hsu, SH; et al. Reciprocal Regulation of MicroRNA-122 and c-Myc in Hepatocellular Cancer: Role of E2F1 and Transcription Factor Dimerization Partner 2. HEPATOLOGY 59:555-566(2014).