TFF2
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Official Full Name
trefoil factor 2
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Overview
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. -
Synonyms
TFF2; trefoil factor 2; SML1, spasmolytic protein 1; spasmolysin; spasmolytic protein 1; spasmolytic polypeptide; SP; SML1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E. coli
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- C
- His
- GST
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- TFF2 Related Articles
- TFF2 Related Research Area
TFF2 involved in several pathways and played different roles in them. We selected most pathways TFF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TFF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
TFF2 has several biochemical functions, for example, CXCR4 chemokine receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFF2 itself. We selected most functions TFF2 had, and list some proteins which have the same functions with TFF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| CXCR4 chemokine receptor binding | |
| protein binding | NHLRC1;RPP30;CCDC88A;EXOC3L;EGR1;PLSCR1;ATXN10;STEAP3;FBXO3 |
TFF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TFF2.
FCRL4; PKM
- Q&As
- Reviews
Q&As (5)
Ask a questionTFF2 promotes the formation of a protective mucous layer on the stomach lining, preventing damage from stomach acid and other harmful factors.
Researchers are exploring various methods of delivering TFF2 protein, including oral administration, to treat gastrointestinal conditions.
TFF2 is being investigated for its potential to reduce inflammation and promote mucosal healing in IBD patients.
Yes, there are ongoing studies exploring the use of TFF2 protein in the treatment of various gastrointestinal disorders.
TFF2 protein-based therapies may offer an alternative or complementary approach to traditional treatments for these conditions.
Customer Reviews (3)
Write a reviewThe manufacturer's technical support can also aid researchers in the data analysis phase.
the manufacturer's technical support is instrumental in assisting researchers throughout their trials.
They can provide valuable guidance in experimental design, optimization, and troubleshooting, helping researchers overcome challenges and maximize the efficiency of their trials.
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