THAP1
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Official Full Name
THAP domain containing, apoptosis associated protein 1
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Overview
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. -
Synonyms
THAP1; THAP domain containing, apoptosis associated protein 1; dystonia 6, torsion (autosomal dominant) , DYT6; 4833431A01Rik; FLJ10477;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
THAP1 involved in several pathways and played different roles in them. We selected most pathways THAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with THAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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THAP1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by THAP1 itself. We selected most functions THAP1 had, and list some proteins which have the same functions with THAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
THAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of THAP1.
NUP62; U2AF2; AP2B1; RALYL; ZCCHC10
- Q&As
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