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THBD

  • Official Full Name

    thrombomodulin

  • Overview

    Thrombomodulin (TM) is a transmembrane glycoprotein composed of 575 amino acids (molecular weight 75 kD with natural anticoagulant properties ( Wen et al, 1987 ). It is normally expressed by a restricted number of cells, such as endothelial and mesothelia
  • Synonyms

    THBD; thrombomodulin; CD141; fetomodulin; CD141 antigen; TM; THRM; AHUS6; BDCA3; THPH12;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Native Proteins
  • Dog
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rabbit
  • Rat
  • Rhesus Macaque
  • CHO
  • E.coli
  • E.coli expression system
  • Endothelial Cell Membrane
  • HEK293
  • HEK293 cells
  • HEK293F
  • Human Cell
  • Human Cells
  • Mammalian Cell
  • Mammalian cells
  • Mammalian Cells
  • C
  • His
  • DYKDDDDK
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • KSI
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human THBD-31177TH Active Recombinant Human THBD protein HEK293 N/A 491 aa
Human THBD-2601H Recombinant Human Thrombomodulin CHO N/A
Human THBD-2743H Recombinant Human THBD protein, His-tagged E.coli His Asp325~Asp481 (Accession # P07204)
Human THBD-31179TH Recombinant Human THBD N/A 491 amino acids
Human THBD-3217H Recombinant Human THBD, His-tagged E.coli His 18-350aa
Human THBD-2744H Recombinant Human THBD protein, His & T7-tagged E.coli His/T7 Val31~Phe169 (Accession # P07204)
Human THBD-138H Recombinant Human THBD Protein, C-His-tagged E.coli C-His
Human THBD-423H Recombinant Human THBD Protein, His-tagged HEK293F N-His Ala19-Ala509
Human THBD-151H Recombinant Human THBD Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human THBD-3575H Recombinant Human THBD protein, His-KSI-tagged E.coli His-KSI 200-500aa
Human THBD-5130H Recombinant Human THBD Protein (Met1-Gly516), C-His tagged Mammalian cells C-His Met1-Gly516
Human THBD-0057H Recombinant Human THBD Protein HEK293 cells
Human THBD-921H Recombinant Human THBD Protein, His-tagged Mammalian Cells His A19-S515
Human THBD-4182H Recombinant Human THBD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human THBD-4182H-B Recombinant Human THBD Protein Pre-coupled Magnetic Beads HEK293
Human THBD-1466H Recombinant Human THBD Protein (Ala19-Ser515), N-GST tagged E.coli N-GST Ala19-Ser515
Human THBD-6442H Recombinant Human THBD Protein (Ala19-Asp486), N-His tagged E.coli N-His Ala19-Asp486
Human THBD-2189H Recombinant Human THBD protein, His-tagged HEK293 His Met1-Ser515
Human THBD-6441H Recombinant Human THBD Protein (Leu10-Asp244), N-His tagged E.coli N-His Leu10-Asp244
Mouse THBD-16735M Recombinant Mouse THBD Protein Mammalian Cell His
Mouse Thbd-2745M Recombinant Mouse Thbd protein, His-tagged E.coli His Val31~Phe167 (Accession # P15306)
Mouse THBD-9181M Recombinant Mouse THBD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse THBD-9181M-B Recombinant Mouse THBD Protein Pre-coupled Magnetic Beads HEK293
Rat Thbd-2747R Recombinant Rat Thbd protein, His-tagged E.coli His Asp324~Asp480 (Accession # O35370)
Rat Thbd-2746R Recombinant Rat Thbd protein, His-tagged E.coli His Val31~Phe167 (Accession # O35370)
Rat Thbd-8787R Recombinant Rat Thbd protein, His-tagged HEK293 His Met1-Ser517
Rat THBD-1220RCL Recombinant Rat THBD cell lysate Human Cell N/A
Rat Thbd-425R Recombinant Rat Thbd Protein, His-tagged HEK293F N-His Ile17-Gly518
Rat Thbd-426R Recombinant Rat Thbd Protein, His-tagged E.coli N-His Ile17-Gly518
Rabbit THBD-306R Active Native Rabbit Lung Thrombomodulin Endothelial Cell Membrane N/A
Rabbit THBD-424R Recombinant Rabbit THBD Protein, His-tagged E.coli N-His Ser66-Pro197
Dog THBD-2742D Recombinant Dog THBD protein, His & GST-tagged E.coli His/GST Arg279~Ser493 (Accession # Q5W7P8)
Homo sapiens (Human) RFL17670HF Recombinant Full Length Human Thrombomodulin(Thbd) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-575)
Mus musculus (Mouse) RFL33540MF Recombinant Full Length Mouse Thrombomodulin(Thbd) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (17-577)
Rhesus Macaque THBD-4697R Recombinant Rhesus monkey THBD Protein, His-tagged Mammalian Cell His
Rhesus Macaque THBD-4511R-B Recombinant Rhesus Macaque THBD Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque THBD-4511R Recombinant Rhesus Macaque THBD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
THBD-2602H Active Recombinant Human Thrombomodulin, His-tagged Mammalian cells His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • THBD Related Articles
  • THBD Related Research Area

THBD involved in several pathways and played different roles in them. We selected most pathways THBD participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with THBD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesPLG;C1QB;C6;MBL2;C1R;SERPINA1E;PLAT;PROC;SERPINA1D

THBD has several biochemical functions, for example, calcium ion binding, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by THBD itself. We selected most functions THBD had, and list some proteins which have the same functions with THBD. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPCDHGA4;EFCAB2;EFCAB7;CDH4;TPT1;FAT1A;PPEF1;PKD1L2;DLB
protein bindingREL;ECE2;TMEM88;COL6A2;SPHK1;RMND5A;CTSH;ADCY6;KIAA0947
receptor activityATP6AP2;PAQR5B;CRTAM;PLXNA1;ANTXR2;PVR;SLC20A2;GUCY1B3;CADM1B
transmembrane signaling receptor activityERBB2;NCR2;FZD3A;TLR2-1;TNFRSF11A;PTH1RA;KLRC2;GPR113;Fzd4

THBD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THBD here. Most of them are supplied by our site. Hope this information will be useful for your research of THBD.

F2; mdtB; dadA; PSENEN

Szarvas, N; Szilagyi, A; et al. First-line therapy in atypical hemolytic uremic syndrome: consideration on infants with a poor prognosis. ITALIAN JOURNAL OF PEDIATRICS 40:-(2014).
Sinibaldi, S; Guzzo, I; et al. Post-transplant recurrence of atypical hemolytic uremic syndrome in a patient with thrombomodulin mutation. PEDIATRIC TRANSPLANTATION 17:E177-E181(2013).
  • Q&As
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