THEM4
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Official Full Name
thioesterase superfamily member 4
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Overview
Carboxyl-terminal modulator protein (CTMP) is a negative regulator of Akt and was identified as an Akt binding protein. Akt, also referred to as PKB or Rac, plays a critical role in controlling the balance between survival and apoptosis. This protein kina -
Synonyms
THEM4; thioesterase superfamily member 4; C terminal modulator protein; CTMP; C-terminal modulator protein; carboxyl-terminal modulator protein; FLJ27206; MGC29636;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | THEM4-1775HCL | Recombinant Human THEM4 cell lysate | N/A |
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| Human | THEM4-1469HFL | Recombinant Full Length Human THEM4 Protein, C-Flag-tagged | Mammalian cells | Flag |
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| Human | THEM4-2190H | Recombinant Human THEM4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Human | THEM4-2190H-B | Recombinant Human THEM4 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | THEM4-16741M | Recombinant Mouse THEM4 Protein | Mammalian Cell | His |
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| Mouse | Them4-6408M | Recombinant Mouse Them4 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | THEM4-9185M-B | Recombinant Mouse THEM4 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | THEM4-9185M | Recombinant Mouse THEM4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | THEM4-6050R | Recombinant Rat THEM4 Protein | Mammalian Cell | His |
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| Rat | THEM4-5707R | Recombinant Rat THEM4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | THEM4-5707R-B | Recombinant Rat THEM4 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- THEM4 Related Articles
THEM4 involved in several pathways and played different roles in them. We selected most pathways THEM4 participated on our site, such as Activation of AKT2, Adaptive Immune System, CD28 co-stimulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with THEM4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Activation of AKT2 | PDPK1A;THEM4 |
| Adaptive Immune System | KIR2DS2;SEC23A;PAG1;FRS2;DZIP3;CREB1B;KIF5A;CMTM2A;NCR3LG1 |
| CD28 co-stimulation | THEM4;MAP3K8;PDPK1A;MAPKAP1 |
| CD28 dependent PI3K/Akt signaling | THEM4;MAPKAP1;PDPK1A;MAP3K8 |
| Costimulation by the CD28 family | BTLA;MAPKAP1;THEM4;MAP3K8;CTLA4;PDPK1A;HLA-DQB2;CSK |
| DAP12 interactions | SPTBN1;PRKAR1AA;PEA15A;DUSP7;SPRED1;DUSP4;KIR3DS1;CSF2RA;PEA15 |
| DAP12 signaling | SPRED2;CNKSR1;CSF2RA;DAB2IPB;DUSP1;SPRED1;SPRED3;DUSP9;THEM4 |
| Downstream signal transduction | CNKSR1;MARK3;SPTA1;PEBP1;FGF8B;CRKL;SPRED1;THEM4;SPRED3 |
THEM4 has several biochemical functions, for example, palmitoyl-CoA hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by THEM4 itself. We selected most functions THEM4 had, and list some proteins which have the same functions with THEM4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| palmitoyl-CoA hydrolase activity | ACOT1;BAAT;THEM4;PPT1;ACOT5;GNPAT;ACOT8;THEM5;ACOT7 |
THEM4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THEM4 here. Most of them are supplied by our site. Hope this information will be useful for your research of THEM4.
AKT1
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