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TICAM2

  • Official Full Name

    toll-like receptor adaptor molecule 2

  • Overview

    TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4; MIM 603030).
  • Synonyms

    TICAM2; toll-like receptor adaptor molecule 2; TIR domain-containing adapter molecule 2; TICAM 2; TIRP; TRAM; cytoplasmic adaptor; TRIF-related adaptor molecule; NF-kappa-B-activating protein 502; toll-like receptor adaptor protein 3; putative NF-kappa-B-;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TICAM2-3230H Recombinant Human TICAM2, GST-tagged E.coli GST 1-235aa
Human TICAM2-1079HCL Recombinant Human TICAM2 293 Cell Lysate HEK293 N/A
Human TICAM2-646H Recombinant Human TICAM2 Protein, His-tagged E.coli His Lys34~Ile241
Human TICAM2-4598H Recombinant Human TICAM2 protein, GST-tagged E.coli GST 2-235aa
Mouse TICAM2-16773M Recombinant Mouse TICAM2 Protein Mammalian Cell His
Mouse Ticam2-6426M Recombinant Mouse Ticam2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Ticam2-647M Recombinant Mouse Ticam2 Protein, His/GST-tagged E.coli His/GST Ser20~Ser196
Mouse TICAM2-9208M Recombinant Mouse TICAM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TICAM2-9208M-B Recombinant Mouse TICAM2 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey TICAM2-1022C Recombinant Cynomolgus TICAM2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey TICAM2-765C Recombinant Cynomolgus Monkey TICAM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey TICAM2-765C-B Recombinant Cynomolgus Monkey TICAM2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TICAM2-4713R Recombinant Rhesus monkey TICAM2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TICAM2-4527R-B Recombinant Rhesus Macaque TICAM2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TICAM2-4527R Recombinant Rhesus Macaque TICAM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TICAM2 Related Research Area

TICAM2 involved in several pathways and played different roles in them. We selected most pathways TICAM2 participated on our site, such as NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TICAM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
NF-kappa B signaling pathwayPIDD1;CXCL12;CFLAR;IL1B;TRADD;CCL4L1;TNFRSF1A;CCL4;DDX58
Toll-like receptor signaling pathwayCCL4L1;CD40;CXCL11;AKT3A;CXCL10;MAPK1;IL12BA;PIK3R3B;AKT2
PertussisIL6;LY96;GM5077;C4BP;TRAF6;IRF3;ITGB1;Il23a;C1RA
Hepatitis BFasl;IKBKB;PIK3CG;BIRC5;EGR3;PIK3R5;PTK2B;CASP12;TGFB1

TICAM2 has several biochemical functions, for example, phospholipid binding, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TICAM2 itself. We selected most functions TICAM2 had, and list some proteins which have the same functions with TICAM2. You can find most of the proteins on our site.

Function Related Protein
phospholipid bindingAGAP1;PACSIN1A;AMPH;PSD4;ANXA1;PRKCI;ANXA9;ABCG1;ARHGAP44
protein bindingZFP110;SNRNP25;HSPB2;MAP4K2;SMARCB1;TRIM40;RHBDD1;C1QTNF3;CITED2
signal transducer activityTAS2R123;HTR1AB;TACR1A;MIER1A;GPR25;TAAR14J;ASZ1;OLFCG5;GNAO1A

TICAM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TICAM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TICAM2.

MEOX2; C; TLR4; IL1R1; TIRAP; TICAM1; IL1RAP; TRAF6; PIAS2; FTH1; Smad6

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