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TJAP1

Official Full Name

tight junction associated protein 1 (peripheral)
Overview

This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alternatively spliced transcript variants have been described. A related pseudogene exists on the X chromosome.
Synonyms

TJAP1; tight junction associated protein 1 (peripheral); tight junction protein 4 (peripheral) , TJP4; tight junction-associated protein 1; PILT; tight junction protein 4 (peripheral); protein incorporated later into tight junctions; TJP4; DKFZp686F06131;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TJAP1-3245H	Recombinant Human TJAP1, GST-tagged	E.coli	GST	1-351aa	$319 / 25ug
Human	TJAP1-1056HCL	Recombinant Human TJAP1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TJAP1-416H	Recombinant Human TJAP1 Protein, His-tagged	E.coli	N-His	Ala4-Gly272	Inquiry
Mouse	Tjap1-417M	Recombinant Mouse Tjap1 Protein, His-tagged	E.coli	N-His	Glu20-Met258	Inquiry
Rat	Tjap1-418R	Recombinant Rat Tjap1 Protein, His-tagged	E.coli	N-His	Met1-Ala225	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TJAP1 Related Articles

TJAP1 involved in several pathways and played different roles in them. We selected most pathways TJAP1 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TJAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Tight junction	CDC42L2;LLGL1;MYH7;MYHZ2;CLDNA;MYL10;TJP1;EPB41L2;CLDN10A

TJAP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TJAP1 itself. We selected most functions TJAP1 had, and list some proteins which have the same functions with TJAP1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	CD86;KIAA0146;C1orf187;PYGL;SPDL1;FBXO25;CD37;ERAP1;HNRNPA1

TJAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TJAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TJAP1.

pagA; q7cg98_yerpe; q81pc9_bacan; glnA

Buckley, MM; O'Halloran, KD; et al. Modulation of enteric neurons by interleukin-6 and corticotropin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome. JOURNAL OF PHYSIOLOGY-LONDON 592:5235-5250(2014).

Thway, K; Fisher, C; et al. Claudin-1 is expressed in perineurioma-like low-grade fibromyxoid sarcoma. HUMAN PATHOLOGY 40:1586-1590(2009).