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TJP2

  • Official Full Name

    tight junction protein 2 (zona occludens 2)

  • Overview

    Tight junctions, or zona occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane protein
  • Synonyms

    TJP2; tight junction protein 2 (zona occludens 2); deafness, autosomal dominant 51 , DFNA51; tight junction protein ZO-2; Friedreich ataxia region gene X104 (tight junction protein ZO 2); X104; ZO 2; ZO2; zonula occludens protein 2; Friedreich ataxia regi;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TJP2-3246H Recombinant Human TJP2, His-tagged E.coli His N-term-289aa
Human TJP2-1055HCL Recombinant Human TJP2 293 Cell Lysate HEK293 N/A
Human TJP2-2188HFL Recombinant Full Length Human TJP2 Protein, C-Flag-tagged Mammalian cells Flag
Human TJP2-6700H Recombinant Human TJP2 Protein (Gly307-Ala669), N-His tagged E.coli N-His Gly307-Ala669
Human TJP2-2198H Recombinant Human TJP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TJP2-2198H-B Recombinant Human TJP2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Tjp2-6441M Recombinant Mouse Tjp2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Chicken TJP2-6480C Recombinant Chicken TJP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TJP2 Related Articles
  • TJP2 Related Signal Pathway

TJP2 involved in several pathways and played different roles in them. We selected most pathways TJP2 participated on our site, such as Tight junction, Vibrio cholerae infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TJP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Tight junctionCTTN;YBX3;MYHZ1.1;PRKCG;CLDN5B;RAB13;MYL5;PTENB;RHOAD
Vibrio cholerae infectionATP6V1E2;SEC61G;ATP6V0A1;ATP6V1F;ATP6V1D;ATP6AP1;ATP6V0D2;TJP2;ACTB

TJP2 has several biochemical functions, for example, guanylate kinase activity, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TJP2 itself. We selected most functions TJP2 had, and list some proteins which have the same functions with TJP2. You can find most of the proteins on our site.

Function Related Protein
guanylate kinase activityDLG3;DLG1;MPP2;MPP3;DLG4B;GUK1;DLG1L;CARD11;GUK1B
protein C-terminus bindingPPM1A;MSH2;ERCC6;MED12;DLG1;KCNK3;PPP2CA;CTNNB1;OPRL1
protein bindingMAGEA6;TAF11;FRK;S100A13;SSSCA1;XRCC2;ZNF599;INPP4B;CERS2
protein binding, bridgingTNNT2A;ANK2;PPP2R3A;CAV1;PPP4R2;STUB1;SLC9A1;FGG;CBX5
protein domain specific bindingWNT1;SKIL;TUBA1A;HMGB2;CTBP1;CALM;ITGA3;ICA1;IPCEF1

TJP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TJP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TJP2.

SCRIB; LASP1; YWHAB; YWHAG; YWHAZ

Wang, HG; Dong, JN; et al. Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic colitis. IMMUNOLOGY 144:254-262(2015).
Ye, P; Yu, H; et al. Expression patterns of tight junction components induced by CD24 in an oral epithelial cell-culture model correlated to affected periodontal tissues. JOURNAL OF PERIODONTAL RESEARCH 49:253-259(2014).
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