TLR7
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Official Full Name
toll-like receptor 7
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Overview
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. -
Synonyms
TLR7; toll-like receptor 7;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Macaca Mulatta (Rhesus Monkey)
- Mouse
- Rhesus Macaque
- Rhesus monkey
- E. coli
- E.coli
- HEK293
- Mammalian Cell
- GST
- hIgG1
- hIgG4
- His
- MYC
- His (Fc)
- Avi
- Myc
- His|T7
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- TLR7 Related Articles
- TLR7 Related Research Area
TLR7 involved in several pathways and played different roles in them. We selected most pathways TLR7 participated on our site, such as Toll-like receptor signaling pathway, Measles, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLR7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Toll-like receptor signaling pathway | MAP2K2B;IFNB1;TLR4BA;LY96;IFNAR2;IL6;IL-8;MAPK8;CD80 |
Measles | PIK3R3;CD209A;CBLB;IL1A;CD46;IL2RA;TRAF6;CCND3;IFNA2 |
Influenza A | PRKCA;PYCARD;MAP2K1;CCL5;PIK3CG;IL18;XPO1;OAS3;MAP2K6 |
TLR7 has several biochemical functions, for example, double-stranded RNA binding, drug binding, siRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TLR7 itself. We selected most functions TLR7 had, and list some proteins which have the same functions with TLR7. You can find most of the proteins on our site.
Function | Related Protein |
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double-stranded RNA binding | OASL1;DHX36;PRKRIP1;HSPD1;RNASEN;DDX58;ADARB1;YRDC;DGCR8 |
drug binding | MTOR;ADH1;DHODH;Alb;CHRNB4;CHKA;TOP2A;NR1I2;CYP2D6 |
siRNA binding | DICER1;MECP2;TLR9;TLR7;TARBP2;AGO2 |
single-stranded RNA binding | LSM14A;TLR8;LONP1;HMGB1;EIF2C3;DDX58;ANXA1;POLR2G;A1CF |
transmembrane signaling receptor activity | GPR124;OR6K3;CALCRLA;KLRB1;CD3D;DCC;VIPR1B;EVI2A;RYK |
TLR7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLR7 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLR7.
a8k1f4_human; MLF1; PSMD2; Hacd3; AARSD1; q7ard3_yerpe; GRAMD1A; MYD88
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Ask a questionCustomer Reviews (3)
Write a reviewManufacturers should provide detailed information about the production process, quality control measures, and purity assessment methods employed.
A reliable manufacturer ensures the production and purification of TLR7 protein, maintaining its quality and purity.
TLR7 protein is an enzyme involved in the digestion of carbohydrates, specifically starch.
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