TMEM43
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Official Full Name
transmembrane protein 43
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Overview
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. -
Synonyms
TMEM43; transmembrane protein 43; DKFZp586G1919; LUMA; MGC3222; ARVC5; ARVD5;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | TMEM43-3289H | Recombinant Human TMEM43, His-tagged | E.coli | His | C-term-314aa | |
| Human | TMEM43-1117H | Recombinant Human TMEM43 | Mammalian Cell | His |
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| Human | TMEM43-950HCL | Recombinant Human TMEM43 293 Cell Lysate | HEK293 | N/A |
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| Human | TMEM43-4214H-B | Recombinant Human TMEM43 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | TMEM43-4214H | Recombinant Human TMEM43 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | TMEM43-17045M | Recombinant Mouse TMEM43 Protein | Mammalian Cell | His |
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| Mouse | TMEM43-9399M | Recombinant Mouse TMEM43 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | TMEM43-9399M-B | Recombinant Mouse TMEM43 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | TMEM43-6170R | Recombinant Rat TMEM43 Protein | Mammalian Cell | His |
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| Rat | TMEM43-5827R-B | Recombinant Rat TMEM43 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | TMEM43-5827R | Recombinant Rat TMEM43 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Homo sapiens (Human) | RFL18823HF | Recombinant Full Length Human Transmembrane Protein 43(Tmem43) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-400) |
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| Mus musculus (Mouse) | RFL7861MF | Recombinant Full Length Mouse Transmembrane Protein 43(Tmem43) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-400) |
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| Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL15184PF | Recombinant Full Length Pongo Abelii Transmembrane Protein 43(Tmem43) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-400) |
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| Rattus norvegicus (Rat) | RFL27862RF | Recombinant Full Length Rat Transmembrane Protein 43(Tmem43) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-400) |
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| Zebrafish | TMEM43-12440Z | Recombinant Zebrafish TMEM43 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
TMEM43 involved in several pathways and played different roles in them. We selected most pathways TMEM43 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TMEM43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
TMEM43 has several biochemical functions, for example, protein binding, protein self-association. Some of the functions are cooperated with other proteins, some of the functions could acted by TMEM43 itself. We selected most functions TMEM43 had, and list some proteins which have the same functions with TMEM43. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ANGPT2;HYI;ZSCAN16;HP;SKAP1;FAM195A;FBXO28;TRIM10;HDC |
| protein self-association | PROSAPIP1;L1CAM;TP53;EPB49;AGXT;VAMP2;MDH2;CCDC88C;S100A7A |
TMEM43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMEM43 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMEM43.
SIAH1; FDFT1; Ktn1; env; CFTR; Rab5c; Bmpr1a; RAB7A; RAB11A; Tmem109; Tnpo1; MMGT1; C1qbp; VAPA; Tmed2; GOLT1B
- Q&As
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