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TMOD2

  • Official Full Name

    tropomodulin 2 (neuronal)

  • Overview

    This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms

    TMOD2; tropomodulin 2 (neuronal); tropomodulin-2; NTMOD; Tropomodulin 2; MGC39481; N Tmod; Neuronal tropomodulin; tropomodulin 2 neuronal; N-TMOD;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TMOD2-3304H Recombinant Human TMOD2, His-tagged E.coli His 1-351aa
Human TMOD2-916HCL Recombinant Human TMOD2 293 Cell Lysate HEK293 N/A
Human TMOD2-5815H Recombinant Human TMOD2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TMOD2-6416H Recombinant Human TMOD2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse TMOD2-17105M Recombinant Mouse TMOD2 Protein Mammalian Cell His
Mouse Tmod2-6523M Recombinant Mouse Tmod2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TMOD2-9447M Recombinant Mouse TMOD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TMOD2-9447M-B Recombinant Mouse TMOD2 Protein Pre-coupled Magnetic Beads HEK293
Rat TMOD2-6183R Recombinant Rat TMOD2 Protein Mammalian Cell His
Rat TMOD2-5840R Recombinant Rat TMOD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TMOD2-5840R-B Recombinant Rat TMOD2 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey TMOD2-1035C Recombinant Cynomolgus TMOD2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey TMOD2-778C Recombinant Cynomolgus Monkey TMOD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey TMOD2-778C-B Recombinant Cynomolgus Monkey TMOD2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TMOD2-4851R Recombinant Rhesus monkey TMOD2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TMOD2-4665R Recombinant Rhesus Macaque TMOD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TMOD2-4665R-B Recombinant Rhesus Macaque TMOD2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TMOD2-1327Z Recombinant Zebrafish TMOD2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TMOD2 Related Articles

TMOD2 involved in several pathways and played different roles in them. We selected most pathways TMOD2 participated on our site, such as Muscle contraction, Striated Muscle Contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMOD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Muscle contractionTNNT3A;TNNI2A.1;TNNT3;MYL6B;DMD;TMOD1;LMOD1;TMOD2;MYL12B
Striated Muscle ContractionDMD;MYBPC1;SMYHC3;TNNT3B;MYBPC2B;DES;TNNT1;TNNI2B.2;TMOD4

TMOD2 has several biochemical functions, for example, actin binding, tropomyosin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMOD2 itself. We selected most functions TMOD2 had, and list some proteins which have the same functions with TMOD2. You can find most of the proteins on our site.

Function Related Protein
actin bindingCNN2;INPPL1B;TNS4;ESPN;PALLD;MYO1G;GCET2;NF2;LIMCH1A
tropomyosin bindingPYCARD;TMOD4;TNNT1;LMOD1;TNNT3;TMOD3;LMOD3;TMOD1;S100A6

TMOD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMOD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMOD2.

Moroz, N; Guillaud, L; et al. Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension. PEERJ 1:-(2013).
Cox-Paulson, EA; Walck-Shannon, E; et al. Tropomodulin Protects alpha-Catenin-Dependent Junctional-Actin Networks under Stress during Epithelial Morphogenesis. CURRENT BIOLOGY 22:1500-1505(2012).
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