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TNPO1
Official Full Name
transportin 1
Background
This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.
Synonyms
TNPO1; transportin 1; transportin-1; importin beta-2; karyopherin beta-2; karyopherin (importin) beta 2; MIP; TRN; IPO2; MIP1; Kpnb2; AU021749; D13Ertd688e