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TOX3

Official Full Name

TOX high mobility group box family member 3
Overview

The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms

TOX3; TOX high mobility group box family member 3; TNRC9, trinucleotide repeat containing 9; CAGF9; trinucleotide repeat containing 9; trinucleotide repeat-containing gene 9 protein; CAG trinucleotide repeat-containing gene F9 protein; TNRC9;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	TOX3-17244M	Recombinant Mouse TOX3 Protein	Mammalian Cell	His	Inquiry
Mouse	TOX3-9527M	Recombinant Mouse TOX3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	TOX3-9527M-B	Recombinant Mouse TOX3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Chicken	TOX3-4734C	Recombinant Chicken TOX3	Mammalian Cell	His	Inquiry
Chicken	TOX3-4733C	Recombinant Chicken TOX3	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

TOX3 involved in several pathways and played different roles in them. We selected most pathways TOX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TOX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TOX3 has several biochemical functions, for example, DNA binding, chromatin binding, estrogen response element binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TOX3 itself. We selected most functions TOX3 had, and list some proteins which have the same functions with TOX3. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	PPP1R10;ZBTB8A;XRCC6;SP2;BRPF1;AHR1A;ADNP2A;LEMD3;MTERFD1
chromatin binding	CIC;TAF2;NCOA5;CUX1;SHMT2;STAT5B;PLAC8;FEZF2;BAHCC1
estrogen response element binding	TRIM24;ESR1;ESR2;TOX3
phosphoprotein binding	MID2;SAG;IGF2R;PKD2;SNCA;FKBP4;TBL2;LYN;PLAT
protein homodimerization activity	DMRTB1;FLRT3;EPHX2;S100A6;CR2;SLK;TBX1;EEA1;BCL2L2

TOX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TOX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TOX3.