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TB

  • Official Full Name

    Tuberculosis

  • Overview

    Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
  • Synonyms

    M. tuberculosis; TB; Tuberculosis; MTB; Mycobacterium tuberculosis;

TB involved in several pathways and played different roles in them. We selected most pathways TB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TB has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TB itself. We selected most functions TB had, and list some proteins which have the same functions with TB. You can find most of the proteins on our site.

Function Related Protein

TB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TB here. Most of them are supplied by our site. Hope this information will be useful for your research of TB.

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