TPPP
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Official Full Name
tubulin polymerization promoting protein
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Overview
May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. -
Synonyms
TPPP; tubulin polymerization promoting protein; tubulin polymerization-promoting protein; brain specific protein p25 alpha; p25; p25alpha; TPPP/p25; TPPP1; 25 kDa brain-specific protein; Glycogen synthase kinase 3 (GSK3) inhibitor p24; OTTHUMP00000161630; p24; p25-alpha; TPPP_HUMAN;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- HEK293F
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
TPPP involved in several pathways and played different roles in them. We selected most pathways TPPP participated on our site, such as Glial Cell Differentiation, Regulation of Microtubule Cytoskeleton, SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TPPP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glial Cell Differentiation | CNP;PLP1;MBP;TPPP;GAP43 |
| Regulation of Microtubule Cytoskeleton | CFL2;MARK1;MARK2;TPPP;DPYSL2;MAP1B;TESK2 |
| SIDS Susceptibility Pathways | PHOX2B;CREM;SP3;CTCF;SST;MECP2;MAZ;KCNH2;TAC1 |
TPPP has several biochemical functions, for example, microtubule binding, protein binding, tubulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TPPP itself. We selected most functions TPPP had, and list some proteins which have the same functions with TPPP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule binding | PAFAH1B1A;KIF20B;MAPRE1A;MTAP6;NUMA1;SPAG8;WHAMM;NDE1;BCL2L11 |
| protein binding | CHDH;HHLA2;MARVELD3;ROPN1L;TMEM140;GBP5;SMPDL3A;RERE;ADAM9 |
| tubulin binding | STMN4;PARK2;TBCC;FYN;VBP1;GPAA1;STMN2A;TTLL4;RABGAP1 |
TPPP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPPP here. Most of them are supplied by our site. Hope this information will be useful for your research of TPPP.
CDK11B; bip; SNCA; SLC6A3
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