TPX2
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Official Full Name
TPX2, microtubule-associated, homolog
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Overview
The TPX2 protein, also known as targeting protein for Xklp1, restricted expression proliferation associated protein p100, and differentially expressed in cancer and non-cancerous lung cells protein 2 (DIL2), is a 100 kD nuclear protein that contains two c -
Synonyms
TPX2; TPX2, microtubule-associated, homolog (Xenopus laevis); C20orf1, C20orf2, chromosome 20 open reading frame 1; targeting protein for Xklp2; DIL 2; p100; protein fls353; differentially expressed in lung cells; TPX2, microtubule-associated protein hom;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Sf9 Insect Cell
- Flag
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | TPX2-7044H | Recombinant Human TPX2, His-tagged | Sf9 Insect Cell | His | Full length | |
Human | TPX2-829HCL | Recombinant Human TPX2 293 Cell Lysate | HEK293 | N/A | ||
Human | TPX2-1921H | Recombinant Human TPX2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | TPX2-222HFL | Active Recombinant Full Length Human TPX2 Protein, C-Flag-tagged | Mammalian cells | Flag | ||
Human | TPX2-2246H | Recombinant Human TPX2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | TPX2-2246H-B | Recombinant Human TPX2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | TPX2-17278M | Recombinant Mouse TPX2 Protein | Mammalian Cell | His | ||
Mouse | Tpx2-6615M | Recombinant Mouse Tpx2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | TPX2-9552M-B | Recombinant Mouse TPX2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | TPX2-9552M | Recombinant Mouse TPX2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Chicken | TPX2-6007C | Recombinant Chicken TPX2 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- TPX2 Related Articles
TPX2 involved in several pathways and played different roles in them. We selected most pathways TPX2 participated on our site, such as Aurora A signaling, Gastric cancer network 1, PLK1 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with TPX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Aurora A signaling | TACC1;AURKB;CENPA;GADD45A;NDEL1;TACC3;OAZ1;TPX2;TDRD7 |
Gastric cancer network 1 | RNF216;ACTL6A;MYBL2;C21orf33;TOP2A;LIN9;ESM1;GATS;SMOC2 |
PLK1 signaling events | TCTN2;TPT1;SPC24;ERCC6L;NDC80;ECT2;PLK1S1;TPX2;BORA |
TPX2 has several biochemical functions, for example, ATP binding, GTP binding, importin-alpha family protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TPX2 itself. We selected most functions TPX2 had, and list some proteins which have the same functions with TPX2. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | TSSK1;ABCB6;PMS2;MYH1E;DMPK;UBE2B;TBCK;UBE2I;JAK2A |
GTP binding | TUBD1;ARL10;RHOV;HHAT;TUBAL3;ARL3;TUBA4A;EHD1B;RAB13 |
importin-alpha family protein binding | GOLGA2;RAN;TPX2 |
protein binding | AMPH;RUNX2;TSPO;MTPAP;STX11;ZKSCAN1;KDM5B;ATP5O;RNF149 |
protein kinase binding | NSF;EEF2;TNIP2;KCNQ3;FOXM1;RHOD;TSACC;TRAF4;GSK3B |
TPX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TPX2.
AURKA; CDK6; NCK1; PIK3R1; CRK; GRB2; Mad2l1; NAP1L1; THAP11; pi3p; Rab7a; AFAP1; CDC5L; SAP130
- Q&As
- Reviews
Q&As (5)
Ask a questionTPX2 interacts with various proteins involved in spindle formation and cell cycle regulation, influencing cellular functions crucial for proper division.
Several drug development efforts are underway to target TPX2, but challenges include ensuring specificity and minimizing off-target effects.
Several clinical trials are exploring the therapeutic potential of targeting TPX2 in cancer treatment, evaluating its role as a molecular target.
Elevated TPX2 expression is often linked to poor prognosis in cancer patients, indicating its potential as a prognostic marker.
Abnormal expression or regulation of TPX2 is associated with various cancers, making it a potential target for cancer therapies aimed at disrupting uncontrolled cell division.
Customer Reviews (3)
Write a reviewThe versatility and efficacy of TPX2 in these applications make it an invaluable tool for researchers.
The TPX2 protein exhibits remarkable performance in Western blotting (WB) experiments.
Researchers can rely on TPX2 to deliver reliable and accurate results in ELISA experiments, ensuring precise measurement and quantification of target proteins.
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