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TRIM25

  • Official Full Name

    tripartite motif containing 25

  • Overview

    TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family, and functions as a ubiquitin ligase. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demo
  • Synonyms

    TRIM25; tripartite motif containing 25; tripartite motif containing 25 , zinc finger protein 147 (estrogen responsive finger protein) , ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; EFP; RNF147; RING finger protein 147; zinc finger protein-147; tripartite mo;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TRIM25-788HCL Recombinant Human TRIM25 293 Cell Lysate HEK293 N/A
Human TRIM25-5098H Recombinant Human TRIM25 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TRIM25-483HFL Recombinant Full Length Human TRIM25 Protein, C-Flag-tagged Mammalian cells Flag
Human TRIM25-2253H Recombinant Human TRIM25 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TRIM25-2253H-B Recombinant Human TRIM25 Protein Pre-coupled Magnetic Beads HEK293
Mouse TRIM25-17350M Recombinant Mouse TRIM25 Protein Mammalian Cell His
Mouse Trim25-6647M Recombinant Mouse Trim25 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TRIM25-9597M Recombinant Mouse TRIM25 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TRIM25-9597M-B Recombinant Mouse TRIM25 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TRIM25-10521Z Recombinant Zebrafish TRIM25 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TRIM25 involved in several pathways and played different roles in them. We selected most pathways TRIM25 participated on our site, such as NF-kappa B signaling pathway, RIG-I-like receptor signaling pathway, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
NF-kappa B signaling pathwayBIRC2;GM10591;TNFRSF13C;CCL4;CD40LG;SYK;CXCL12;TNFSF14;LRDD
RIG-I-like receptor signaling pathwayDDX3;MAPK12;MAPK13;CXCL10;IFNA5;MAPK8;CASP10;RNF125;OTUD5A
Influenza AOAS1;TYK2;DDX39B;TLR4;AKT1;ICAM1;IFNA17;NUP98;FURIN

TRIM25 has several biochemical functions, for example, acid-amino acid ligase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM25 itself. We selected most functions TRIM25 had, and list some proteins which have the same functions with TRIM25. You can find most of the proteins on our site.

Function Related Protein
acid-amino acid ligase activityRNF41;TRIM25;UBA3;RAG1
poly(A) RNA bindingSART1;SUPT6H;EIF4G3;RPS24;ZC3H14;MRPL20;ZFC3H1;SMC1A;HELZ2
protein bindingRAB3B;RNF175;RALGDS;DSG1A;ZCCHC11;AMBP;KCNJ3;ELMO1;TP53BP1
transcription factor activity, sequence-specific DNA bindingTEFB;GATAD2A;RXRGA;NR1D4B;RFX2;ASCL1B;SMAD3;SIM2;NKX2-1
ubiquitin protein ligase activity involved in ERAD pathwaySYVN1;TMEM129;RNF5;STUB1;RNF185;PARK2;TRIM25;AMFR
zinc ion bindingTRIM24;UQCRC2A;NEURL1AA;ADAM10A;LMO4A;MT2;FBXO11;MMP23B;CSRP2

TRIM25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM25 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM25.

DDX58; NS; f1ba49_9viru; NS1; NS1; NS1; NS1; XRCC3; IGF1R; APC

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