TRIP13
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Official Full Name
thyroid hormone receptor interactor 13
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Overview
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. -
Synonyms
TRIP13; thyroid hormone receptor interactor 13; pachytene checkpoint protein 2 homolog; 16E1BP; thyroid receptor interacting protein 13; 16E1-BP; Homo sapiens HPV16 E1 protein binding protein mRNA complete cds; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; Human papillomavirus type 16 E1 protein binding protein; Human papillomavirus type 16 E1 protein-binding protein; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13; TRP13_HUMAN;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Strep
- N/A
- No tag
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
TRIP13 involved in several pathways and played different roles in them. We selected most pathways TRIP13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIP13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
TRIP13 has several biochemical functions, for example, ATP binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIP13 itself. We selected most functions TRIP13 had, and list some proteins which have the same functions with TRIP13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | UBE2E1;PANK3;LONP1;ABCG5;JAK2A;CLK4;TAF1;PAPSS2;NSFA |
| identical protein binding | CRYBB2;WRNIP1;PVRL2;VIM;CLDN3;TPRG1L;PRKAB2;LRRK2;ACADM |
| protein binding | EVC2;DHRS1;MRPL45;NAT2;E2F2;SP3;PDS5A;ASAP1;OIP5 |
| transcription cofactor activity | SUPT20H;TMF1;SLC26A3;KAT2B;PTPN14;MED24;WDR75;CALCOCO1;LPXN |
TRIP13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIP13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIP13.
LASP1; GLYCTK; LOXL4; MAD2L1BP
- Q&As
- Reviews
Q&As (7)
Ask a questionTRIP13 plays a role in DNA repair, contributing to genomic stability and integrity.
Altered TRIP13 activity is linked with cancer progression due to its role in cell cycle regulation.
TRIP13 is crucial for the regulation of the cell cycle, particularly in the transition between different phases.
Targeting TRIP13 could provide a novel approach in cancer treatment, focusing on its role in cell cycle regulation.
Mutations in TRIP13 can lead to errors in cell division and increased genomic instability.
It assists in proper chromosome segregation, ensuring accurate cell division during mitosis.
TRIP13 works with other proteins to coordinate cell cycle progression and DNA repair processes.
Customer Reviews (3)
Write a reviewDependable for data accuracy. Aids research productivity.
Precision in analysis. Supports our research consistently.
Efficient and timely service. Critical for research progress.
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