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TRPC1

  • Official Full Name

    transient receptor potential cation channel, subfamily C, member 1

  • Overview

    Transient receptor potential channel 1 (TRPC1) is a protein that in humans is encoded by the TRPC1 gene.
  • Synonyms

    trpc1; transient receptor potential cation channel, subfamily C, member 1; HTRP 1; HTRP1; MGC133334; MGC133335; Mtrp1; Short transient receptor potential channel 1; Transient receptor potential cation channel subfamily C member 1; Transient receptor potential channel 1; Transient receptor protein 1; TRP 1; TRP 1 protein; Trp related protein 1; TRP-1; TRP1; TRP1 protein; Trpc1 transient receptor potential cation channel subfamily C member 1; TRPC1_HUMAN; Trrp1; transient receptor potential protein; xtrpc1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • In vitro E. coli expression system
  • Mammalian Cell
  • C
  • His
  • His (Fc)
  • Avi
  • Flag
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TRPC1-746HCL Recombinant Human TRPC1 293 Cell Lysate HEK293 N/A
Human TRPC1-3387H Recombinant Human TRPC1 protein, His-tagged E.coli His 1-383 aa
Human TRPC1-1157HFL Recombinant Human TRPC1 protein, His&Flag-tagged HEK293 His&Flag 1-793 aa
Human TRPC1-2776H Recombinant Human TRPC1 protein(31-100 aa), C-His-tagged E. coli C-His 31-100 aa
Mouse Trpc1-1326M Recombinant Mouse Trpc1 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-793aa
Rat TRPC1-6299R Recombinant Rat TRPC1 Protein Mammalian Cell His
Rat TRPC1-5956R Recombinant Rat TRPC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TRPC1-5956R-B Recombinant Rat TRPC1 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL11934BF Recombinant Full Length Bovine Short Transient Receptor Potential Channel 1(Trpc1) Protein, His-Tagged E.coli expression system His Full Length (1-793)
Mus musculus (Mouse) RFL36736MF Recombinant Full Length Mouse Short Transient Receptor Potential Channel 1(Trpc1) Protein, His-Tagged E.coli expression system His Full Length (1-793aa)
Oryctolagus cuniculus (Rabbit) RFL19923OF Recombinant Full Length Rabbit Short Transient Receptor Potential Channel 1(Trpc1) Protein, His-Tagged E.coli expression system His Full Length (1-759)
Rattus norvegicus (Rat) RFL17363RF Recombinant Full Length Rat Short Transient Receptor Potential Channel 1(Trpc1) Protein, His-Tagged E.coli expression system His Full Length (1-759)
Rhesus Macaque TRPC1-4987R Recombinant Rhesus monkey TRPC1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TRPC1-4801R-B Recombinant Rhesus Macaque TRPC1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TRPC1-4801R Recombinant Rhesus Macaque TRPC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TRPC1-7834Z Recombinant Zebrafish TRPC1 Mammalian Cell His
Chicken TRPC1-1227C Recombinant Chicken TRPC1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TRPC1 Related Articles

TRPC1 involved in several pathways and played different roles in them. We selected most pathways TRPC1 participated on our site, such as Glutamatergic synapse, Serotonergic synapse, Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutamatergic synapseGRIK4;GNG12;GRIA2;Adcy4;GRM3;GRIK2;PLA2G4D;GRM5;GRIN3A
Serotonergic synapseHTR1B;Casp3;HTR1E;GNG5;PRKACA;HTR6;GNB4;HTR1F;CYP2J5
Pancreatic secretionPLA2G1B;CA2;CELA3B;KCNMA1;PRSS2;RAB3D;RAC1;Car2;PLA2G10

TRPC1 has several biochemical functions, for example, calcium channel activity, cation channel activity, inositol 1,4,5 trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPC1 itself. We selected most functions TRPC1 had, and list some proteins which have the same functions with TRPC1. You can find most of the proteins on our site.

Function Related Protein
calcium channel activityCACNG7A;CACNA1BA;CACNG8A;CACNA1DA;RYR2;TRPC5A;TRPV2;TRPC1;TRPM8
cation channel activityMCOLN1;P2RX1;CALHM2;ASIC4A;FAM26E;TRPV4;ASIC3;TRPM1B;TRPM1A
inositol 1,4,5 trisphosphate bindingAKR1C1;PLCL1;RPH3A;TRPC3;CYTH2;TRPC6;TRPC2;TRPC5A;TRPC7A
ion channel bindingS100A10;KCNJ11;LYN;KCNC1;ARRB1;DLG1;USP10;EPN1;AP2M1
protein bindingPFKM;VAV3;CDH5;NSMCE1;CYFIP2;EGFR;XRCC3;VEGFAA;CCDC68
store-operated calcium channel activityZP3;ORAI1B;TRPC5;TRPC7A;ORAI2;TRPC4;TRPC1;TRPC3;TRPC2B

TRPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPC1.

PKD2; MX1; q81xd6_bacan; o68752_yerpe; cya; yegQ; purL; carB; q5nel7_fratt; q5ni33_fratt; metE; q7cgs8_yerpe; pepP; ygfz_yerpe; proS; q7ch26_yerpe; q7chb5_yerpe; icmF1

Tran, VT; Ho, PT; et al. Mechanotransduction Channels of the Trabecular Meshwork. CURRENT EYE RESEARCH 39:291-303(2014).
Liu, YW; Schneider, MF; et al. FGF2 activates TRPC and Ca2+ signaling leading to satellite cell activation. FRONTIERS IN PHYSIOLOGY 5:-(2014).
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