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TRPC7

Official Full Name

transient receptor potential cation channel, subfamily C, member 7
Overview

Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name.
Synonyms

TRPC7; transient receptor potential cation channel, subfamily C, member 7; short transient receptor potential channel 7; Capacitative calcium channel TRPC7; cation channel, subfamily C, member 7; hTRP7; KNP3; Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7; mTRP7; Putative capacitative calcium channel; Transient receptor potential cation channel subfamily C member 7; transient receptor potential-related channel 7, a novel putative Ca2+ channel protein; Transient receptor protein 7; TRP 7; TRP-7; TRP7 protein; TRPC 7; Trpc7 transient receptor potential cation channel, subfamily C, member 7; TRPC7_HUMAN; TRPM2; Trrp8; OTTHUMP00000221120; OTTHUMP00000221122; OTTHUMP00000221124; OTTHUMP00000221125; likley ortholog of mouse transient receptor potential c; TRP7;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TRPC7-3433H	Recombinant Human TRPC7, His-tagged	E.coli	His	721-781aa	$319 / 25ug
Human	TRPC7-740HCL	Recombinant Human TRPC7 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TRPC7-1163HFL	Recombinant Human TRPC7 protein, His&Flag-tagged	HEK293	His&Flag	1-746 aa	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TRPC7 Related Articles

TRPC7 involved in several pathways and played different roles in them. We selected most pathways TRPC7 participated on our site, such as Axon guidance, Developmental Biology, Effects of PIP2 hydrolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Axon guidance	DUSP6;FGF20A;DCX;FRS2A;GDNF;ABL1;SEMA6D;COL4A3;PAQR3A
Developmental Biology	INSM1B;EFNB2A;MED9;EPHA2A;EFNA1A;INSM1A;LGI2;JAK3;HELZ2
Effects of PIP2 hydrolysis	TAE1;DGKQ;RASGRP2;TRPC3;DGKG;ABHD12;DGKB;DGKA;MGLL
Elevation of cytosolic Ca2+ levels	TRPC7;TRPC6A;TRPC3
G alpha (q) signalling events	PROK1;TAC1;NPFF;TAC2;PROKR2;OXTRL;DGKB;OPN4A;FPR-RS4
GPCR downstream signaling	TRPC3;SOUL4;PTGDR2;GNA13;ARHGEF17;ADRA2C;HRH3;LPAR1;PTH2
Gastrin-CREB signalling pathway via PKC and MAPK	UTS2D;NMS;OPN4;ARHGEF25;GPR132;CCK;QRFPR;DGKB;PROKR1A
Hemostasis	SLC16A8;ANXA2;KIFC1;DOCK8;GLG1B;CABLES2;GRB14;RAPGEF4;CD84

TRPC7 has several biochemical functions, for example, inositol 1,4,5 trisphosphate binding, protein binding, store-operated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPC7 itself. We selected most functions TRPC7 had, and list some proteins which have the same functions with TRPC7. You can find most of the proteins on our site.

Function	Related Protein
inositol 1,4,5 trisphosphate binding	TRPC7A;ITPR3;TRPC5A;TRPC5;TRPC2B;CYTH2;TRPC2;TRPC7;TRPC6
protein binding	SLC30A2;KCTD1;HYAL3;GRIFIN;TOP2A;ERCC6L;UBE2D3;FAM124B;SPHK1
store-operated calcium channel activity	TRPC6A;TRPC2;ORAI2;ORAI3;TRPC5A;TRPC6;TRPC5;TRPC4;ORAI1B

TRPC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPC7.

MX1

Tabarean, IV; et al. Persistent Histamine Excitation of Glutamatergic Preoptic Neurons. PLOS ONE 7:-(2012).

Cvetkovic-Lopes, V; Eggermann, E; et al. Rat Hypocretin/Orexin Neurons Are Maintained in a Depolarized State by TRPC Channels. PLOS ONE 5:-(2010).