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TRPM7

Official Full Name

transient receptor potential cation channel, subfamily M, member 7
Overview

TRPs, mammalian homologs of the Drosophila transient receptor potential (TRP) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutant.
Synonyms

TRPM7; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential cation channel subfamily M member 7; CHAK1; LTRPC7; TRP PLIK; LTrpC-7; channel-kinase 1; LTRPC ion channel family member 7; long transient receptor pot;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TRPM7-46H	Active Recombinant Human TRPM7(1180-end) Protein, N-His-tagged	Sf21	His	1180-end	Inquiry
Human	TRPM7-1169HFL	Recombinant Human TRPM7 protein, His&Flag-tagged	HEK293	His&Flag	1-1865 aa	Inquiry
Rat	Trpm7-344R	Recombinant Rat Trpm7 Protein, His-tagged	E.coli	His	Ile19~Gly179	$298 / 10ug
Zebrafish	TRPM7-3201Z	Recombinant Zebrafish TRPM7	Mammalian Cell	His		Inquiry
Chicken	TRPM7-4086C	Recombinant Chicken TRPM7	Mammalian Cell	His		Inquiry

TRPM7 Related Articles

TRPM7 involved in several pathways and played different roles in them. We selected most pathways TRPM7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TRPM7 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TRPM7 itself. We selected most functions TRPM7 had, and list some proteins which have the same functions with TRPM7. You can find most of the proteins on our site.

Function	Related Protein

TRPM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPM7.

Kim, TY; Shin, SK; et al. Identification of the phosphorylation sites on intact TRPM7 channels from mammalian cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 417:1030-1034(2012).

Gilliam, JC; Wensel, TG; et al. TRP channel gene expression in the mouse retina. VISION RESEARCH 51:2440-2452(2011).