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TSPAN12

  • Official Full Name

    tetraspanin 12

  • Overview

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
  • Synonyms

    TSPAN12; tetraspanin 12; TM4SF12, transmembrane 4 superfamily member 12; tetraspanin-12; NET 2; AI663988; TSPAN 12; 9030619E17; AI426782; AW111457; MGC109305; NET2; OTTHUMP00000211224; Tetraspan NET 2; Tetraspanin12; TM4SF12; Transmembrane 4 superfamily member 12; tspan-12; tetraspan NET-2; EVR5; NET-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Gallus gallus (Chicken)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TSPAN12-3455H Recombinant Human TSPAN12, GST-tagged E.coli GST 111-224aa
Human TSPAN12-707HCL Recombinant Human TSPAN12 lysate HEK293 N/A
Human TSPAN12-2735H Recombinant Human TSPAN12 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TSPAN12-211H Recombinant Human TSPAN12 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Mouse TSPAN12-17502M Recombinant Mouse TSPAN12 Protein Mammalian Cell His
Mouse Tspan12-6689M Recombinant Mouse Tspan12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TSPAN12-9681M Recombinant Mouse TSPAN12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TSPAN12-9681M-B Recombinant Mouse TSPAN12 Protein Pre-coupled Magnetic Beads HEK293
Rat TSPAN12-6324R Recombinant Rat TSPAN12 Protein Mammalian Cell His
Rat TSPAN12-5980R Recombinant Rat TSPAN12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TSPAN12-5980R-B Recombinant Rat TSPAN12 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL19315BF Recombinant Full Length Bovine Tetraspanin-12(Tspan12) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Gallus gallus (Chicken) RFL17354GF Recombinant Full Length Chicken Tetraspanin-12(Tspan12) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Homo sapiens (Human) RFL21853HF Recombinant Full Length Human Tetraspanin-12(Tspan12) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Mus musculus (Mouse) RFL32500MF Recombinant Full Length Mouse Tetraspanin-12(Tspan12) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Rattus norvegicus (Rat) RFL10837RF Recombinant Full Length Rat Tetraspanin-12(Tspan12) Protein, His-Tagged E.coli expression system His Full Length (1-305)
Zebrafish TSPAN12-11371Z Recombinant Zebrafish TSPAN12 Mammalian Cell His
Chicken TSPAN12-1774C Recombinant Chicken TSPAN12 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TSPAN12 Related Articles
  • TSPAN12 Related Research Area

TSPAN12 involved in several pathways and played different roles in them. We selected most pathways TSPAN12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TSPAN12 has several biochemical functions, for example, NOT Wnt-activated receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN12 itself. We selected most functions TSPAN12 had, and list some proteins which have the same functions with TSPAN12. You can find most of the proteins on our site.

Function Related Protein
NOT Wnt-activated receptor activitySFRP1B;SFRP1A;SFRP1;SFRP4;FRZB;TSPAN12;SFRP2;SZL;SETD6
protein bindingPAX6;FGF12;BRAT1;LGR6;KHDRBS1;KRT16;ITGA7;IL10RA;CNBP

TSPAN12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN12 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN12.

TFCP2; q5ngw2_fratt; NDP; FZD4

Pagel, JM; Spurgeon, SE; et al. Otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, for relapsed or refractory NHL patients. BRITISH JOURNAL OF HAEMATOLOGY 168:38-45(2015).
Gopal, AK; Tarantolo, SR; et al. Phase 1b study of otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, in combination with rituximab and bendamustine in relapsed indolent lymphoma patients. INVESTIGATIONAL NEW DRUGS 32:1213-1225(2014).
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